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3d rendered image of highly pathogenic avian influenza

MCDC Announces “Increased Micro Sampling to Monitor Immunological Response” RPP

The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA), has issued a new Request for Prototype Proposals (RPP) through the Medical CBRN Defense Consortium (MCDC). “Increased Micro Sampling to Monitor Immunological Response” (IMMIR) seeks to improve our ability to monitor immune responses to vaccination, which is critical for accelerating vaccine […]

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digital rendering of antigens

MCDC Releases “Defined Rapid Antigen Identification and Immunogenic Characterization” RPP

The U.S. Department of Defense (DoD), through the Joint Science and Technology Office (JSTO) Defense Threat Reduction Agency (DTRA), has released a new Request for Prototype Proposals (RPP-25-07) under the Medical CBRN Defense Consortium (MCDC). This Request for Project Proposals, titled “Defined Rapid Antigen Identification and Immunogenic Characterization” (DRAIIC), aims to increase protection against infectious

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Medicine manufacturing assembly line.

ARPA-H’s Scalable Solutions ISO

Mission Office Innovative Solutions Opening (ISO)– ARPA-H-SOL-24-105 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) officially released solicitation ARPA-H-SOL-24-105 under its Scalable Solutions Office (SSO), titled Mission Office Innovative Solutions Opening (ISO). This initiative aims to fuel bold, high-impact biomedical and health innovations that tackle persistent barriers in health

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Medicine production on conveyor belt

IBMSC RISE OTA Consortium RFI

Request for Information – IBMSC Resilient Industry and Supply Chain Enterprise (RISE) OTA Consortium In June 2025, the U.S. Department of Health and Human Services (HHS) issued a Request for Information (RFI) through the Administration for Strategic Preparedness and Response’s (ASPR) Center for Industrial Base Management and Supply Chain (IBMSC). This RFI invites feedback from

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DARPA’s Ag x BTO Special Topic Calls for Agricultural Defense Innovations

DARPA’s Ag x BTO Special Topic Calls for Agricultural Defense Innovations

Special Topic: Ag x BTO To defend against threats to America’s agricultural infrastructure, the Defense Advanced Research Projects Agency (DARPA) has launched a new Special Topic Area (STA) through its Biological Technologies Office (BTO). Known as Ag x BTO, this initiative seeks to catalyze innovative approaches to defending the U.S. agricultural system from chemical, biological,

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Doctor holding augmented reality medical-related digital icons

ARPA-H Resilient Systems ISO

RESILIENT SYSTEMS OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-103 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Innovative Solutions Opening (ISO) under the Resilient Systems Office (RSO), under Solicitation Number ARPA-H-SOL-24-103. a mission-focused solicitation designed to confront systemic challenges across

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Digital composite image of scientific experiment and dNA strands

ARPA-H Health Science Futures ISO

Health Science Futures – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) ARPA-H-SOL-24-104 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO), under Solicitation Number ARPA-H-SOL-24-104. As part of its mission to catalyze high-risk, high-reward research,

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ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

On June 6, 2025, the Advanced Research Projects Agency for Health (ARPA-H) issued Amendment 02 to its four flagship Innovation Solutions Opening (ISO) solicitations: Health Science Futures (HSF), Proactive Health Office (PHO), Resilient Systems Office (RSO), and Scalable Solutions Office (SSO). These ISOs represent the core operational arms of ARPA-H’s mission to fund transformative, high-risk,

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Vaccine Research

Strengthening National Preparedness: BARDA’s FY23 Modernized BAA

Strengthening National Preparedness: BARDA’s FY23 Modernized BAA BAA-23-100-SOL-00004 – Office of Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA) In response to today’s evolving public health landscape, the Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services (HHS) within the Administration for Strategic

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Superconductor microchip with blue overlay

Unlocking Scientific Breakthroughs for National Security: DARPA’s DSO Office-wide BAA

Broad Agency Announcement Defense Sciences Office (DSO) Office-wide BAA Defense Sciences Office HR001125S0013 Pioneering the Next Generation of Defense Research On June 3, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Defense Sciences Office (DSO), announced an open solicitation under Broad Agency Announcement (BAA) HR001125S0013. This office-wide BAA serves as a mechanism for

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Rapid Response Test

BARDA’s DxR2 RPP: Scaling Biothreat Diagnostic Readiness

In a continued effort to bolster national preparedness against emerging biological threats, the Biomedical Advanced Research and Development Authority (BARDA) has released the Phase 2 issue of the “Biothreat Diagnostic Rapid Response” Solicitation (RPP-25-06-DxR2) on May 29, 2025, under its Rapid Response Partnership Vehicle (RRPV). BARDA is seeking to address pressing gaps in diagnostic test

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radiation voltaics

Rads to Watts Proposers Day

Program Overview Rads to Watts is a DARPA program dedicated to pioneering innovative methods for directly converting nuclear radiation into electricity, with a primary emphasis on radiation voltaics (also known as radiovoltaics). The program’s long-term goal is to develop radiovoltaic systems capable of transforming high-power nuclear radiation into kilowatts of electrical energy. Achieving operation at

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