Max Higgins, Senior Consultant, Author at EverGlade

Max Higgins, Senior Consultant

Max Higgins, Senior Consultant

ARPA-H Launches SURPASS to Advance Simulation-Augmented, Real-Time Adaptive Clinical Trials

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The Advanced Research Projects Agency for Health’s (ARPA-H) Proactive Health Office has released Innovative Solutions Opening (ISO) ARPA-H SOL 26 164 for the Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) program. SURPASS seeks to establish persistent, multi-arm clinical trial platforms that integrate simulation, accumulating human data, prespecified adaptations, shared operational infrastructure, and reusable regulatory assets.

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BARDA’s “Protection Before Day One” Initiative Seeks Broadly Protective Influenza Vaccines

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The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a draft Request for Project Proposals (RPP) for “Protection Before Day One” (PBD1), Solicitation No. RRPV 26-08-PBD1. The initiative seeks to close a central pandemic preparedness gap: the time between identifying a novel pandemic influenza strain and deploying

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BARDA’s Draft New Vaccine Platforms RPP Signals a Major Push for Adaptable Medical Countermeasures

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Updated to reflect Draft Version 2, issued September 24, 2026. The revised draft expands eligible pathogen targets, clarifies platform maturity requirements, and adds a preference for U.S.-based companies and domestic performance. Requirements remain subject to change in the final RPP. The Biomedical Advanced Research and Development Authority (BARDA) has released the draft Request for Project

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DARPA Firefox Seeks Scalable Technologies for High-Resolution, Noninvasive Brain-Computer Interface

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Download the Solicitation The Defense Advanced Research Projects Agency’s (DARPA) Biological Technologies Office (BTO) has released the Firefox Program Solicitation, DARPA-PS-26-137, to advance a scalable, noninvasive brain-computer interface (BCI). The program seeks to build on DARPA’s existing coherent optical sensing system by addressing two scale up barriers: steering coherent light across multiple neural sensing regions

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ARPA-H COSMOS Initiative Seeks to Test Whether Space Can Accelerate Regenerative Drug Development

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The Advanced Research Projects Agency for Health (ARPA-H) has released ARPA-H-SOL-26-165, an Innovative Solutions Opening (ISO) for Comprehensive Organ System Modeling in Outer Space (COSMOS). The program will test a consequential hypothesis for the emerging low Earth orbit (LEO) bioeconomy: whether microgravity accelerates aging-related changes in human tissues quickly enough to make autonomous, space based

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ARPA-H UNIQUE: Advancing Quantum Derived Biomedical Imaging

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Updated to reflect Amendment 1, issued on September 24, 2026. The Advanced Research Projects Agency for Health (ARPA-H) has released Innovative Solutions Opening (ISO), UNifying Imaging with QUantum Entanglement* (UNIQUE). The program seeks to determine whether quantum derived observables from 511 keV photon pairs including quantum correlations, correlation loss or decoherence, and positronium sensitive interactions

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DARPA Announces HUBBLE Proposers Day to Map the Human Interactome

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has issued Special Notice DARPA-SN-26-121 announcing a Proposers Day for the planned “High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators” (HUBBLE) program. HUBBLE targets one of the most consequential unsolved problems in computational biology: building an in-silico capability to map all

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ARPA-H STREAM Program: A New Federal Push for Safer, Smarter Weed Management

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The Advanced Research Projects Agency for Health (ARPA-H) has launched the Systems for Tracking and Resilience in Efficient Agricultural-input Management (STREAM) program, a new effort focused on reducing herbicide exposure across the food system without making farming less productive or food less affordable. STREAM starts with a practical problem: herbicides remain essential tools for many

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BARDA’s BioMaP-Consortium Seeks Vendor Managed Inventory Capabilities to Secure the Nation’s API Reserve

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The Biomedical Advanced Research and Development Authority (BARDA), through the Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium), has released Request for Project Proposals (RPP) 26-12-VMI, “Ensuring American Pharmaceutical Supply Chain Resilience through Vendor Managed Inventory Capabilities for Active Pharmaceutical Ingredients Used in Medical Countermeasure Finished Dose Form Drug Products.” Issued by the Administration for Strategic Preparedness and

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ARPA-H’s BRAINS Initiative to Advance Functional Brain Tissue Repair

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Download the Solicitation Restoring Brain Function: ARPA-H’s BRAINS Initiative The Advanced Research Projects Agency for Health (ARPA-H) has launched the Brain Repair of Any Injured Neural Structure (BRAINS) initiative to address a major unmet need in neurological care: the lack of effective therapies to replace damaged or degenerated brain tissue and restore lost function. Brain

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BARDA Seeks Input on Medical Countermeasures for Drug-Resistant Fungal Infections

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) to better understand the current development landscape for antifungal medical countermeasures. BARDA plays a central role in advancing

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BARDA Seeks Input on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Filovirus Therapeutics

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) focused on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses. Filoviruses, including Ebola virus (EBOV), Sudan virus

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