ARPA-H

The Advanced Research Projects Agency for Health (ARPA‑H) has released Special Notice ARPA‑H‑SN‑26‑158 for ASCENT‑IBO: Accelerating Safe Clinical Evaluation of Novel Treatments – Ibogaine for Better Outcomes in OUD. This effort sits under the Proactive Health Office (PHO) Innovative Solutions Opening (ISO ARPA‑H‑SOL‑24‑106) and is directly tied to Executive Order 14401, which directs federal agencies

The Advanced Research Projects Agency for Health (ARPA‑H) has released Special Notice ARPA‑H‑SN‑26‑156 under its Proactive Health Office (PHO), focusing on early clinical development of ibogaine for opioid use disorder (OUD).  This Special Notice sits under ARPA‑H’s Proactive Health Office Innovative Solutions Opening (ISO PHO‑SOL‑24‑106), which is an open solicitation for “revolutionary solutions” that do not

Download the Solicitation Why ARPA-H is Seeking Solutions for Sleep Health The Advanced Research Projects Agency for Health (ARPA-H), through its Proactive Health Office (PHO), has released an Innovative Solutions Opening (ISO) for the Restorative and health-Enhancing Sleep Time (REST) program (ARPA-H-SOL-26-159). REST seeks to fundamentally change how sleep quality is measured, diagnosed, and treated by

Download the Solicitation Restoring Brain Function: ARPA-H’s BRAINS Initiative The Advanced Research Projects Agency for Health (ARPA-H) has launched the Brain Repair of Any Injured Neural Structure (BRAINS) initiative to address a major unmet need in neurological care: the lack of effective therapies to replace damaged or degenerated brain tissue and restore lost function. Brain

Download the Solicitation The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Mission Office, has released a Sources Sought notice titled “Novel and Enhanced Modalities for Optic Nerve Imaging” (ARPA-H-SS-26-157). This request is being issued in support of ARPA-H’s Transplantation of Human Eye Allografts (THEA) program, an ambitious initiative focused on

DOWNLOAD THE SOLICITATION The Advanced Research Projects Agency for Health (ARPA-H) has released the Intelligent Generator of Research (IGoR) Innovative Solutions Opening (ISO), a bold initiative designed to fundamentally transform how biomedical research is conducted. Managed through ARPA-H’s Proactive Health Office, the program seeks to address longstanding inefficiencies in scientific discovery by creating an artificial

DOWNLOAD THE SOLICITATION ARPA-H’s new Technology InteGrator and AcceleratoR (TIGAR) Innovative Solutions Opening (ISO) is a tightly scoped opportunity for government contractors and their research partners to reshape how complex biologics, tissues, and organs are stored, transported, and deployed at scale. By seeding high-risk, high-impact biopreservation concepts, TIGAR aims to unlock temperature-flexible storage for increasingly

STOMP_ISO_ARPA-H-SOL-26-152 The Advanced Research Projects Agency for Health (ARPA-H) has released an Innovative Solutions Opening (ISO) for the Systematic Targeting of Microplastics (STOMP) program, signaling a major federal investment in understanding and addressing the health impacts of micro- and nano-plastics (MNPs). As mounting evidence links MNP exposure to a range of adverse health outcomes, ARPA-H

1-CURE_ISO_ARPA-H-SOL-26-147 Cancer remains one of the leading causes of death globally, with existing treatment modalities often limited by cost, accessibility, and effectiveness, particularly for metastatic disease. In response, the Advanced Research Projects Agency for Health (ARPA-H) has released an Innovative Solutions Opening (ISO) under solicitation ARPA-H-SOL-26-147 for the One Comprehensive Universal Radiotherapy for Everyone (1-CURE)