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DARPA Announces HUBBLE Proposers Day to Map the Human Interactome

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has issued Special Notice DARPA-SN-26-121 announcing a Proposers Day for the planned “High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators” (HUBBLE) program. HUBBLE targets one of the most consequential unsolved problems in computational biology: building an in-silico capability to map all […]

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OSC Launches NSFF Program to Scale Private Investment in Critical Minerals

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The Office of Strategic Capital (OSC) has released a Notice of Funding Opportunity for its new National Security Fund Finance (NSFF) Program, a fund-level financing initiative designed to attract and scale private capital for critical minerals and materials supply chains vital to U.S. national security. The opportunity is directed at qualified, professionally managed debt investment

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DARPA Firefox Program to Explore High-Channel, Noninvasive Brain-Computer Interfaces

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), is hosting a Firefox Proposers Day in support of a planned Firefox Program Solicitation. Firefox seeks to advance coherent optical technologies that could enable a scalable, noninvasive brain-computer interface, or BCI, with single-neuron spatiotemporal resolution. The Special Notice is not yet a

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BARDA Previews TACTIC Program for Threat-Agnostic CBRN Therapeutics

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The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a pre-solicitation notice for a potential future project opportunity: TACTIC, or Threat-Agnostic CBRN Therapeutics. The anticipated effort would support development of therapeutics that address host dysregulation caused by chemical, biological, radiological, and nuclear, or CBRN, threats. BARDA is

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BARDA’s Draft New Vaccine Platforms RPP Signals a Major Push for Adaptable Medical Countermeasures

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The Biomedical Advanced Research and Development Authority (BARDA) has released a draft Request for Project Proposals (RPP), RRPV 26-05-NVP: “New Vaccine Platforms,” through the Rapid Response Partnership Vehicle (RRPV). The draft opportunity seeks mature, adaptable vaccine platform technologies that can help the United States prepare for emerging infectious disease threats before and during public health

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BARDA Releases RFP for Pandemic Influenza Vaccine Medical Countermeasures

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The Biomedical Advanced Research and Development Authority (BARDA) has released a new Request for Proposals, Vaccine Medical Countermeasures for Pandemic Influenza Preparedness and Response. The solicitation seeks partners to support the development, manufacturing, stockpiling, regulatory readiness, and rapid deployment of influenza vaccine medical countermeasures during a pandemic or other public health emergency. BARDA’s objective is

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NSF’s $1.5B Foundational Research Funds: Where the Next Wave of Science and Technology Will Start

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The U.S. National Science Foundation has released 12 new Notices of Funding Opportunity totaling more than $1.5 billion for foundational research. The announcements span biological sciences, computing, engineering, geosciences, mathematics, materials, physics, chemistry, and astronomy. This is not a single funding program, and it should not be read as one. It is a coordinated signal

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ARPA-H STREAM Program: A New Federal Push for Safer, Smarter Weed Management

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The Advanced Research Projects Agency for Health (ARPA-H) has launched the Systems for Tracking and Resilience in Efficient Agricultural-input Management (STREAM) program, a new effort focused on reducing herbicide exposure across the food system without making farming less productive or food less affordable. STREAM starts with a practical problem: herbicides remain essential tools for many

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BARDA’s BioMaP-Consortium Seeks Vendor Managed Inventory Capabilities to Secure the Nation’s API Reserve

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The Biomedical Advanced Research and Development Authority (BARDA), through the Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium), has released Request for Project Proposals (RPP) 26-12-VMI, “Ensuring American Pharmaceutical Supply Chain Resilience through Vendor Managed Inventory Capabilities for Active Pharmaceutical Ingredients Used in Medical Countermeasure Finished Dose Form Drug Products.” Issued by the Administration for Strategic Preparedness and

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BARDA’s Next Big Investment Play: Pandemic Preparedness And Domestic Manufacturing

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The Biomedical Advanced Research and Development Authority (BARDA) has been telegraphing its priorities for years, but the latest cluster of moves makes the picture sharper: the U.S. is shifting from “buy vaccines when a crisis hits” to owning the infrastructure that keeps pandemic response on a hair trigger. Three signals stand out: A new pre‑solicitation

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MTEC’s FY26 Multi‑Topic RPP: Where Military Medicine, Prevention, And Infectious Disease Innovation Converge

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The Medical Technology Enterprise Consortium (MTEC) has released its Fiscal Year 2026 Multi‑Topic Request for Project Proposals (MTEC‑26‑04‑MultiTopic), opening a wide lane for medical prototype and knowledge solutions that directly support force health and readiness. Enhanced White Papers are due October 30, 2026 at noon Eastern, and awards will be made under MTEC’s prototype OTA

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DARPA Releases Official Solicitation for Protein ENGineering (PENG)

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The Defense Advanced Research Projects Agency (DARPA), under the Defense Sciences Office (DSO), has released the full Program Solicitation for Protein ENGineering (PENG), DARPA-PS-26-129. The solicitation moves PENG from concept and Proposers Day into an active, multi‑phase program seeking innovative proposals to build a multifunctional, target‑agnostic platform for precise, programmable editing of endogenous proteins. PENG’s

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