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ARPA-H Announces the Functional Repair of Neocortical Tissue (FRONT) Program

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Functional Repair of Neocortical Tissue (FRONT) Health Science Futures (HSF) Innovative Solutions Opening (ISO) ARPA-H-SOL-25-120 July 10, 2025 Restoring the Damaged Brain: ARPA-H’s FRONT Program Targets Functional Neocortical Repair The Advanced Research Projects Agency for Health (ARPA-H) has announced an ambitious new program under its Health Science Futures (HSF) office: the Functional Repair of Neocortical […]

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BARDA’s Call to Action Antibiotics for Treatment of Bacterial Pneumonia or Bloodstream Infections

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Combating Resistant Infections: BARDA’s Push for Advanced Antibiotics The Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services (HHS), has released a pre-solicitation notice aimed at identifying qualified vendors to support the late-stage development, procurement, and stockpiling of antibiotics for critical public health threats. Targeted programs include

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DTRA ONTARGET: Platforms to Accelerate Novel Medical Countermeasure Development for CBRN Threats

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The U.S. Department of Defense (DoD), through the Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND), has released a Request for Prototype Proposals (RPP-25-06) under the Medical CBRN Defense Consortium (MCDC) under OTA W15QKN-16-9-1002. This new initiative, Operationalizing Novel Technologies for Advanced Rapid Generation of Effective Medical Countermeasures (ONTARGET), is looking

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MCDC Announces “Increased Micro Sampling to Monitor Immunological Response” RPP

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The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA), has issued a new Request for Prototype Proposals (RPP) through the Medical CBRN Defense Consortium (MCDC). “Increased Micro Sampling to Monitor Immunological Response” (IMMIR) seeks to improve our ability to monitor immune responses to vaccination, which is critical for accelerating vaccine

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MCDC Releases “Defined Rapid Antigen Identification and Immunogenic Characterization” RPP

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The U.S. Department of Defense (DoD), through the Joint Science and Technology Office (JSTO) Defense Threat Reduction Agency (DTRA), has released a new Request for Prototype Proposals (RPP-25-07) under the Medical CBRN Defense Consortium (MCDC). This Request for Project Proposals, titled “Defined Rapid Antigen Identification and Immunogenic Characterization” (DRAIIC), aims to increase protection against infectious

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ARPA-H’s Scalable Solutions ISO

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Mission Office Innovative Solutions Opening (ISO)– ARPA-H-SOL-24-105 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) officially released solicitation ARPA-H-SOL-24-105 under its Scalable Solutions Office (SSO), titled Mission Office Innovative Solutions Opening (ISO). This initiative aims to fuel bold, high-impact biomedical and health innovations that tackle persistent barriers in health

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IBMSC RISE OTA Consortium RFI

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Request for Information – IBMSC Resilient Industry and Supply Chain Enterprise (RISE) OTA Consortium In June 2025, the U.S. Department of Health and Human Services (HHS) issued a Request for Information (RFI) through the Administration for Strategic Preparedness and Response’s (ASPR) Center for Industrial Base Management and Supply Chain (IBMSC). This RFI invites feedback from

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ARPA-H’s Proactive Health Office ISO Amendment 2

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PROACTIVE HEALTH OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-106 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has recently amended the Proactive Health Office (PHO) Innovative Solutions Opening (ISO). The PHO ISO invites novel and disruptive health innovations aimed at extending health spans and improving health

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ARPA-H Resilient Systems ISO

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RESILIENT SYSTEMS OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-103 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Innovative Solutions Opening (ISO) under the Resilient Systems Office (RSO), under Solicitation Number ARPA-H-SOL-24-103. a mission-focused solicitation designed to confront systemic challenges across

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Unlocking Scientific Breakthroughs for National Security: DARPA’s DSO Office-wide BAA

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Broad Agency Announcement Defense Sciences Office (DSO) Office-wide BAA Defense Sciences Office HR001125S0013 Pioneering the Next Generation of Defense Research On June 3, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Defense Sciences Office (DSO), announced an open solicitation under Broad Agency Announcement (BAA) HR001125S0013. This office-wide BAA serves as a mechanism for

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BARDA’s DxR2 RPP: Scaling Biothreat Diagnostic Readiness

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In a continued effort to bolster national preparedness against emerging biological threats, the Biomedical Advanced Research and Development Authority (BARDA) has released the Phase 2 issue of the “Biothreat Diagnostic Rapid Response” Solicitation (RPP-25-06-DxR2) on May 29, 2025, under its Rapid Response Partnership Vehicle (RRPV). BARDA is seeking to address pressing gaps in diagnostic test

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radiation voltaics

Rads to Watts Proposers Day

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Program Overview Rads to Watts is a DARPA program dedicated to pioneering innovative methods for directly converting nuclear radiation into electricity, with a primary emphasis on radiation voltaics (also known as radiovoltaics). The program’s long-term goal is to develop radiovoltaic systems capable of transforming high-power nuclear radiation into kilowatts of electrical energy. Achieving operation at

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