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Life Sciences

NIAID Renews IMPAc‑TB to Accelerate Tuberculosis Vaccine Development 

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Overview of the Opportunity The National Institute of Allergy and Infectious Diseases (NIAID), through the National Institutes of Health (NIH), has issued RFP No. BAA-75N93026R00008 for the Immune Mechanisms of Protection Against Mycobacterium tuberculosis Center (IMPAc‑TB), a five‑year contract program that renews the effort to accelerate TB vaccine development. The goal is to define tissue‑specific and […]

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BARDA’s RFI Explores Repurposing Autoinjector Equipment for New Drug Delivery Devices 

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Download the Solicitation Overview of the RFI The Biomedical Advanced Research and Development Authority (BARDA) is looking at a specific problem: how to repurpose specialized equipment originally designed to manufacture an emergency autoinjector platform into a broader drug delivery solution. Through the Rapid Response Partnership Vehicle (RRPV), BARDA released a new Request for Information (RFI), “Repurposing Equipment

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BARDA Issues RFI on Adjuvanted Egg-Based Influenza Vaccine for Pandemic Preparedness 

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Download the Solicitation Overview of the RFI The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a Request for Information (RFI) titled “Advanced Clinical Development and Licensure of an Adjuvanted Egg-based Influenza Vaccine.” Through this market research effort, BARDA is seeking feedback from industry, academia, and other stakeholders to

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The Escalating Bundibugyo Ebola Outbreak and the $1.4 Billion Push for Biodefense Funding

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Since early May, a severe outbreak of the Bundibugyo strain of the Ebola virus (a type of filovirus) has spread rapidly through the Democratic Republic of the Congo and neighboring Uganda. With over 1,000 confirmed infections and more than 290 fatalities already recorded across multiple nations, the second largest Ebola outbreak on record crossed a

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The End of Mega Labs? What the Proposed NIH Grant Cap Means for Universities

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For decades, the biomedical research landscape has been dominated by a relatively small number of highly funded, high-profile laboratories. It is a system that tends to reward past success with future funding. But a newly proposed policy from the National Institutes of Health (NIH) could fundamentally reshape how federal research dollars flow through the U.S.

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DTRA-Backed MTEC Opportunity for Field Manufacturing of PCR Primers and Probes

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Download the Solicitation Overview of the RPP The Medical Technology Enterprise Consortium (MTEC), in support of the Defense Threat Reduction Agency (DTRA), has released a Request for Project Proposals (RPP) titled PRimer and prObe Manufacturing PlaTform (PROMPT) (Solicitation Number: MTEC-26-03-PROMPT). Through this solicitation, MTEC is seeking proposals from qualified organizations to develop a fully automated, man-portable, and ruggedized prototype platform for

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DARPA Seeks Input on Advancing Autonomous Science for Biological Applications RFI

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Overview of the RFI The Defense Advanced Research Projects Agency (DARPA), through its Biological Technology Office (BTO), has released a Request for Information (RFI) titled “Advancing Autonomous Science for Biological Applications” (Special Notice DARPA-SN-26-96). Through this market research effort, DARPA is seeking feedback from industry, academia, and other stakeholders to better understand the current state of

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ARPA-H Launches REST to Transform Sleep Through Home-Based Sleep Diagnostics and Treatment

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Download the Solicitation Why ARPA-H is Seeking Solutions for Sleep Health The Advanced Research Projects Agency for Health (ARPA-H), through its Proactive Health Office (PHO), has released an Innovative Solutions Opening (ISO) for the Restorative and health-Enhancing Sleep Time (REST) program (ARPA-H-SOL-26-159). REST seeks to fundamentally change how sleep quality is measured, diagnosed, and treated by

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BARDA Seeks Input on Next-Generation High-Performance Antigen Diagnostics

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Download the Solicitation Overview of the RFI The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a Request for Information (RFI) titled “High Performance Antigen Diagnostics.” Through this market research effort, BARDA is seeking feedback from industry, academia, and other stakeholders to better understand the landscape of current and emerging high-performance immunoassay

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BARDA Issues RFP Under Project BioShield for 2-PAM Autoinjectors to Strengthen Chemical Threat Preparedness 

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR), has released a Request for Proposals (RFP) for 2-PAM Autoinjectors for Project BioShield. The RFP supports late-stage clinical development, regulatory approval, procurement, and delivery of pralidoxime, also known as 2-PAM, autoinjectors for the treatment of organophosphate (OP)

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BARDA Releases BundiVx Solicitation to Accelerate Bundibugyo Ebola Vaccine Development

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has officially released Request for Project Proposals (RPP) RRPV 26-13-BundiVx for the Bundibugyo Virus Outbreak Response Vaccines (BundiVx) Program. The solicitation seeks to accelerate the development of investigational vaccine candidates targeting Bundibugyo ebolavirus (BDBV), the virus responsible for

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ARPA-H’s BRAINS Initiative to Advance Functional Brain Tissue Repair

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Download the Solicitation Restoring Brain Function: ARPA-H’s BRAINS Initiative The Advanced Research Projects Agency for Health (ARPA-H) has launched the Brain Repair of Any Injured Neural Structure (BRAINS) initiative to address a major unmet need in neurological care: the lack of effective therapies to replace damaged or degenerated brain tissue and restore lost function. Brain

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