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ARPA-H Announces the Functional Repair of Neocortical Tissue (FRONT) Program

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Functional Repair of Neocortical Tissue (FRONT) Health Science Futures (HSF) Innovative Solutions Opening (ISO) ARPA-H-SOL-25-120 July 10, 2025 Restoring the Damaged Brain: ARPA-H’s FRONT Program Targets Functional Neocortical Repair The Advanced Research Projects Agency for Health (ARPA-H) has announced an ambitious new program under its Health Science Futures (HSF) office: the Functional Repair of Neocortical

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BARDAs Strategic Investment in Enzymatic Debridement Products

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Advancing Burn Care Preparedness: BARDA’s Strategic Investment in Enzymatic Debridement Products In its ongoing mission to strengthen the nation’s biodefense and emergency response infrastructure, the Biomedical Advanced Research and Development Authority (BARDA), an office within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services, has released a

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BARDA’s Call to Action Antibiotics for Treatment of Bacterial Pneumonia or Bloodstream Infections

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Combating Resistant Infections: BARDA’s Push for Advanced Antibiotics The Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services (HHS), has released a pre-solicitation notice aimed at identifying qualified vendors to support the late-stage development, procurement, and stockpiling of antibiotics for critical public health threats. Targeted programs include

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Vaccine Development

BARDA’s Call to Action on Marburg and Sudan Virus Vaccines

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Preparing for the Next Biological Threat: BARDA’s Vaccine Initiative for MARV and SUDV The Biomedical Advanced Research and Development Authority (BARDA), operating under the U.S. Department of Health and Human Services (HHS), has issued a pre-solicitation notice signaling its intent to launch a major Request for Proposal (RFP) later this year. This effort, managed by

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MCDC Announces “Increased Micro Sampling to Monitor Immunological Response” RPP

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The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA), has issued a new Request for Prototype Proposals (RPP) through the Medical CBRN Defense Consortium (MCDC). “Increased Micro Sampling to Monitor Immunological Response” (IMMIR) seeks to improve our ability to monitor immune responses to vaccination, which is critical for accelerating vaccine

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MCDC Releases “Defined Rapid Antigen Identification and Immunogenic Characterization” RPP

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The U.S. Department of Defense (DoD), through the Joint Science and Technology Office (JSTO) Defense Threat Reduction Agency (DTRA), has released a new Request for Prototype Proposals (RPP-25-07) under the Medical CBRN Defense Consortium (MCDC). This Request for Project Proposals, titled “Defined Rapid Antigen Identification and Immunogenic Characterization” (DRAIIC), aims to increase protection against infectious

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ARPA-H’s Scalable Solutions ISO

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Mission Office Innovative Solutions Opening (ISO)– ARPA-H-SOL-24-105 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) officially released solicitation ARPA-H-SOL-24-105 under its Scalable Solutions Office (SSO), titled Mission Office Innovative Solutions Opening (ISO). This initiative aims to fuel bold, high-impact biomedical and health innovations that tackle persistent barriers in health

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IBMSC RISE OTA Consortium RFI

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Request for Information – IBMSC Resilient Industry and Supply Chain Enterprise (RISE) OTA Consortium In June 2025, the U.S. Department of Health and Human Services (HHS) issued a Request for Information (RFI) through the Administration for Strategic Preparedness and Response’s (ASPR) Center for Industrial Base Management and Supply Chain (IBMSC). This RFI invites feedback from

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ARPA-H Resilient Systems ISO

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RESILIENT SYSTEMS OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-103 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Innovative Solutions Opening (ISO) under the Resilient Systems Office (RSO), under Solicitation Number ARPA-H-SOL-24-103. a mission-focused solicitation designed to confront systemic challenges across

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ARPA-H Health Science Futures ISO

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Health Science Futures – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) ARPA-H-SOL-24-104 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO), under Solicitation Number ARPA-H-SOL-24-104. As part of its mission to catalyze high-risk, high-reward research,

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ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

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On June 6, 2025, the Advanced Research Projects Agency for Health (ARPA-H) issued Amendment 02 to its four flagship Innovation Solutions Opening (ISO) solicitations: Health Science Futures (HSF), Proactive Health Office (PHO), Resilient Systems Office (RSO), and Scalable Solutions Office (SSO). These ISOs represent the core operational arms of ARPA-H’s mission to fund transformative, high-risk,

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Vaccine Research

Strengthening National Preparedness: BARDA’s FY23 Modernized BAA

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Strengthening National Preparedness: BARDA’s FY23 Modernized BAA BAA-23-100-SOL-00004 – Office of Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA) In response to today’s evolving public health landscape, the Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services (HHS) within the Administration for Strategic

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