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Life Sciences

ARPA‑H’s ASCENT‑IBO Initiative: Accelerating Ibogaine Trials For Opioid Use Disorder

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The Advanced Research Projects Agency for Health (ARPA‑H) has released Special Notice ARPA‑H‑SN‑26‑158 for ASCENT‑IBO: Accelerating Safe Clinical Evaluation of Novel Treatments – Ibogaine for Better Outcomes in OUD. This effort sits under the Proactive Health Office (PHO) Innovative Solutions Opening (ISO ARPA‑H‑SOL‑24‑106) and is directly tied to Executive Order 14401, which directs federal agencies

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BARDA Signals Major NPIVS Contract For Pandemic Influenza Vaccines And Adjuvants

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The Biomedical Advanced Research and Development Authority (BARDA) has quietly dropped a pre‑solicitation notice for a major, long‑term contract to sustain and expand the Vaccine Medical Countermeasures (MCMs) for Pandemic Influenza Preparedness and Response Program, including the U.S. National Pre‑pandemic Influenza Vaccine Stockpile (NPIVS). The notice, posted July 30, 2026 under solicitation number 75A50126R00001, is

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Coming Soon From ARPA-H: FASTPASS For Rapid Screening of Medicines  

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The Advanced Research Projects Agency for Health (ARPA‑H) is launching the Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and Supplies (FASTPASS) program to tackle a critical, often invisible problem in the U.S. healthcare system: substandard and contaminated medicines slipping through the supply chain. Drug-related morbidity and mortality cost the system an estimated $528 billion per year and recalls affect the

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ARPA-H Releases FASTPASS For Rapid Screening of Medicines

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The Advanced Research Projects Agency for Health (ARPA‑H) has officially launched the Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and Supplies (FASTPASS) program to tackle a critical, often invisible problem in the U.S. healthcare system: substandard and contaminated medicines slipping through the supply chain. Drug-related morbidity and mortality cost the system an estimated $528 billion per year and

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BARDA Seeks Advanced Dermal Regeneration Solutions for Severe Burns

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The Biomedical Advanced Research and Development Authority (BARDA) has issued a Sources Sought Notice titled “Advanced Dermal Regeneration Substitutes for Treatment of Severe Burns and Complex Traumatic Injuries” (BARDA-CBRN-07282026) to identify commercially available or near commercial technologies that address large-area skin loss from burns and traumatic injuries in a mass casualty setting. This notice is for

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DARPA Announces PENG Program for Programmable Protein Engineering

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The Defense Advanced Research Projects Agency (DARPA) has issued a Special Notice for a new Defense Sciences Office (DSO) program, Protein ENGineering (PENG), and is hosting a hybrid Proposers Day on August 10, 2026, in Arlington, VA, with a webcast option for virtual attendees. DARPA expects to publish the full program solicitation by the end

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NIH’s Unified Funding Strategy Signals a New Approach to Award Decisions

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The National Institutes of Health (NIH) is starting to roll out its new Unified Funding Strategy, originally announced in late 2025, to support more informed, transparent, and flexible funding decisions across its Institutes, Centers, and Offices. Peer review remains central to NIH’s process, but funding decisions will now draw on the full body of review

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ASPR’s New Five Year Plan: Reading the Fine Print on Medical Countermeasure Funding

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The Administration for Strategic Preparedness and Response (ASPR) has quietly dropped one of the most important funding documents of the year: the 2025–2029 Public Health Emergency Medical Countermeasure Enterprise (PHEMCE) Multiyear Budget (MYB). On paper, it is a five‑year budget plan across: The Administration for Strategic Preparedness and Response (ASPR) The Biomedical Advanced Research and

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ARPA-H’s Special Notice Supports Executive Order on Serious Mental Illness and OUD

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The Advanced Research Projects Agency for Health (ARPA‑H) has released Special Notice ARPA‑H‑SN‑26‑156 under its Proactive Health Office (PHO), focusing on early clinical development of ibogaine for opioid use disorder (OUD).  This Special Notice sits under ARPA‑H’s Proactive Health Office Innovative Solutions Opening (ISO PHO‑SOL‑24‑106), which is an open solicitation for “revolutionary solutions” that do not

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HHS & VA’s MOU is Building the Data & Regulatory Backbone for Veterans’ Mental Health 

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The Departments of Health and Human Services (HHS) and Veterans Affairs (VA) have entered a five‑year Memorandum of Understanding (MOU) to coordinate on rapid‑acting treatments for substance use disorders and mental health conditions in veterans, including psychedelic drug products.  In parallel, the HHS/FDA and VA have signed MOU 225‑26‑007, which lays out how the agencies will collaborate and share information

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New DARPA RFI: Multiscale Reasoning Across Human Physiology

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released RFI DARPA‑SN‑26‑100 on “Multiscale Reasoning for Human Physiology.” The agency is seeking input from organizations that can connect human biology from molecules to clinical outcomes in support of military medicine. The focus is on prediction, diagnosis, intervention, and recovery in

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BARDA RRPV RFI Seeks Partners for BSL4 Studies and Support Services 

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Overview of the Opportunity The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a new Request for Information (RFI) titled “Biosafety Level 4 Preclinical and Nonclinical Support for Medical Countermeasure Development (BSL4)”. Issued July 9, 2026, the RFI is a market research exercise to map out who can deliver preclinical and nonclinical

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