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BARDA Previews TACTIC Program for Threat-Agnostic CBRN Therapeutics

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The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a pre-solicitation notice for a potential future project opportunity: TACTIC, or Threat-Agnostic CBRN Therapeutics. The anticipated effort would support development of therapeutics that address host dysregulation caused by chemical, biological, radiological, and nuclear, or CBRN, threats. BARDA is […]

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MTEC’s FY26 Multi‑Topic RPP: Where Military Medicine, Prevention, And Infectious Disease Innovation Converge

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The Medical Technology Enterprise Consortium (MTEC) has released its Fiscal Year 2026 Multi‑Topic Request for Project Proposals (MTEC‑26‑04‑MultiTopic), opening a wide lane for medical prototype and knowledge solutions that directly support force health and readiness. Enhanced White Papers are due October 30, 2026 at noon Eastern, and awards will be made under MTEC’s prototype OTA

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DARPA Releases Official Solicitation for Protein ENGineering (PENG)

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The Defense Advanced Research Projects Agency (DARPA), under the Defense Sciences Office (DSO), has released the full Program Solicitation for Protein ENGineering (PENG), DARPA-PS-26-129. The solicitation moves PENG from concept and Proposers Day into an active, multi‑phase program seeking innovative proposals to build a multifunctional, target‑agnostic platform for precise, programmable editing of endogenous proteins. PENG’s

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DARPA Launches PINPOINT Program To Break The GPS Dependency

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The Defense Advanced Research Projects Agency (DARPA), under the Defense Sciences Office (DSO), has released a Broad Agency Announcement (BAA) for the Precision Inertial Navigation & Positioning On an Integrated Tesseract (PINPOINT) program, HR001126S0016. PINPOINT aims to deliver a new class of micro‑scale inertial measurement units (IMUs) that can provide GPS‑quality positioning and navigation over

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DTRA Topic Call 7: Advanced Bioaerosol Triggers and Engineered Genome Detection

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The Defense Threat Reduction Agency (DTRA), under the Department of Defense, has updated its FY2022–2026 Chemical / Biological Technologies Broad Agency Announcement (BAA HDTRA122S0002) with Topic Call 7, adding two new applied research topics in biological threat detection. The BAA is an open, five-year contracting vehicle focused on Technology Readiness Level (TRL) 3–6 technologies, meaning

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DTRA-Backed MTEC Opportunity for Field Manufacturing of PCR Primers and Probes

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Download the Solicitation Overview of the RPP The Medical Technology Enterprise Consortium (MTEC), in support of the Defense Threat Reduction Agency (DTRA), has released a Request for Project Proposals (RPP) titled PRimer and prObe Manufacturing PlaTform (PROMPT) (Solicitation Number: MTEC-26-03-PROMPT). Through this solicitation, MTEC is seeking proposals from qualified organizations to develop a fully automated, man-portable, and ruggedized prototype platform for

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BARDA Issues RFP Under Project BioShield for 2-PAM Autoinjectors to Strengthen Chemical Threat Preparedness 

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR), has released a Request for Proposals (RFP) for 2-PAM Autoinjectors for Project BioShield. The RFP supports late-stage clinical development, regulatory approval, procurement, and delivery of pralidoxime, also known as 2-PAM, autoinjectors for the treatment of organophosphate (OP)

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DARPA and NSF Launch AI Forge Initiative for University-Led National Security AI Research

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Download the Solicitation The Defense Advanced Research Projects Agency (DARPA), in partnership with the National Science Foundation (NSF) and the Center for AI Standards and Innovation (CAISI) at the National Institute of Standards and Technology (NIST), has released a Request for Information (RFI) for the AI Forge Program. This initiative seeks to identify the capabilities

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DARPA Releases TA1/TA2 Solicitation for RAPIID Blood Analog Systems for Far-Forward Trauma Care

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released Program Solicitation DARPA-PS-26-124 for the Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) program. RAPIID aims to develop a deployable blood analog system capable of providing the life-saving functions of stored whole blood without requiring cold-chain storage or donor logistics. This

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MCDC RFI mNGS Solutions

MCDC Seeks Portable mNGS Solutions for Rapid Pathogen Detection

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MCDC-RFI-Agnostic-Metagenomic-Next-Generation-Sequencing-for-Clinical-Diagnostics Overview of Solicitation The Medical CBRN Defense Consortium (MCDC), managed by Advanced Technology International (ATI) in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND), has released a Request for Information (RFI) titled Agnostic Metagenomic Next-Generation Sequencing (mNGS) for Clinical Diagnostics. Unlike traditional targeted assays, which require

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MCDC RFI Host-Based Diagnostics

MCDC’s Host-Based Diagnostics for Acute Infections RFI

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MCDC Request for Information HOST-BASED DIAGNOSTICS Final A Shift Toward Host-Response Diagnostics The Medical CBRN Defense Consortium (MCDC), managed by Advanced Technology International (ATI), has released a Request for Information (RFI) titled Host-Based Diagnostics for Acute Infections. Issued in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND),

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MCDC Host-Directed Therapeutics Initiative

MCDC’s Host-Directed Therapeutics Initiative

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The Medical Chemical, Biological, Radiological, and Nuclear Defense Consortium (MCDC), managed by Advanced Technology International (ATI), has issued a Request for Information (RFI) focused on “Host-Directed Medical Countermeasures.” This effort, led in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND), represents an early step toward shaping a

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