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DARPA Announces PENG Program for Programmable Protein Engineering

The Defense Advanced Research Projects Agency (DARPA) has issued a Special Notice for a new Defense Sciences Office (DSO) program, Protein ENGineering (PENG), and is hosting a hybrid Proposers Day on August 10, 2026, in Arlington, VA, with a webcast option for virtual attendees. DARPA expects to publish the full program solicitation by the end […]

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NSFF: The Pentagon’s New Fund-Level Play for Critical Minerals Finance

The Department of War’s Office of Strategic Capital (OSC) has announced the National Security Fund Finance (NSFF) program, a new credit initiative aimed at shoring up U.S. critical minerals and materials that sit behind core national security technologies. Rather than adding another grant or project-level loan program for operators, NSFF routes Pentagon capital into the

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DTRA Topic Call 7: Advanced Bioaerosol Triggers and Engineered Genome Detection

The Defense Threat Reduction Agency (DTRA), under the Department of Defense, has updated its FY2022–2026 Chemical / Biological Technologies Broad Agency Announcement (BAA HDTRA122S0002) with Topic Call 7, adding two new applied research topics in biological threat detection. The BAA is an open, five-year contracting vehicle focused on Technology Readiness Level (TRL) 3–6 technologies, meaning

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DTRA-Backed MTEC Opportunity for Field Manufacturing of PCR Primers and Probes

Download the Solicitation Overview of the RPP The Medical Technology Enterprise Consortium (MTEC), in support of the Defense Threat Reduction Agency (DTRA), has released a Request for Project Proposals (RPP) titled PRimer and prObe Manufacturing PlaTform (PROMPT) (Solicitation Number: MTEC-26-03-PROMPT). Through this solicitation, MTEC is seeking proposals from qualified organizations to develop a fully automated, man-portable, and ruggedized prototype platform for

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BARDA Issues RFP Under Project BioShield for 2-PAM Autoinjectors to Strengthen Chemical Threat Preparedness 

Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR), has released a Request for Proposals (RFP) for 2-PAM Autoinjectors for Project BioShield. The RFP supports late-stage clinical development, regulatory approval, procurement, and delivery of pralidoxime, also known as 2-PAM, autoinjectors for the treatment of organophosphate (OP)

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DARPA and NSF Launch AI Forge Initiative for University-Led National Security AI Research

Download the Solicitation The Defense Advanced Research Projects Agency (DARPA), in partnership with the National Science Foundation (NSF) and the Center for AI Standards and Innovation (CAISI) at the National Institute of Standards and Technology (NIST), has released a Request for Information (RFI) for the AI Forge Program. This initiative seeks to identify the capabilities

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DARPA Releases TA1/TA2 Solicitation for RAPIID Blood Analog Systems for Far-Forward Trauma Care

The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released Program Solicitation DARPA-PS-26-124 for the Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) program. RAPIID aims to develop a deployable blood analog system capable of providing the life-saving functions of stored whole blood without requiring cold-chain storage or donor logistics. This

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MCDC RFI mNGS Solutions

MCDC Seeks Portable mNGS Solutions for Rapid Pathogen Detection

MCDC-RFI-Agnostic-Metagenomic-Next-Generation-Sequencing-for-Clinical-Diagnostics Overview of Solicitation The Medical CBRN Defense Consortium (MCDC), managed by Advanced Technology International (ATI) in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND), has released a Request for Information (RFI) titled Agnostic Metagenomic Next-Generation Sequencing (mNGS) for Clinical Diagnostics. Unlike traditional targeted assays, which require

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MCDC RFI Host-Based Diagnostics

MCDC’s Host-Based Diagnostics for Acute Infections RFI

MCDC Request for Information HOST-BASED DIAGNOSTICS Final A Shift Toward Host-Response Diagnostics The Medical CBRN Defense Consortium (MCDC), managed by Advanced Technology International (ATI), has released a Request for Information (RFI) titled Host-Based Diagnostics for Acute Infections. Issued in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND),

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MCDC Host-Directed Therapeutics Initiative

MCDC’s Host-Directed Therapeutics Initiative

The Medical Chemical, Biological, Radiological, and Nuclear Defense Consortium (MCDC), managed by Advanced Technology International (ATI), has issued a Request for Information (RFI) focused on “Host-Directed Medical Countermeasures.” This effort, led in support of the Capability Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND), represents an early step toward shaping a

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