RESILIENT SYSTEMS OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-103 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Innovative Solutions Opening (ISO) under the Resilient Systems Office (RSO), under Solicitation Number ARPA-H-SOL-24-103. a mission-focused solicitation designed to confront systemic challenges across
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Health Science Futures – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) ARPA-H-SOL-24-104 – Amendment 03: October 14, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO), under Solicitation Number ARPA-H-SOL-24-104. As part of its mission to catalyze high-risk, high-reward research,
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On June 6, 2025, the Advanced Research Projects Agency for Health (ARPA-H) issued Amendment 02 to its four flagship Innovation Solutions Opening (ISO) solicitations: Health Science Futures (HSF), Proactive Health Office (PHO), Resilient Systems Office (RSO), and Scalable Solutions Office (SSO). These ISOs represent the core operational arms of ARPA-H’s mission to fund transformative, high-risk,
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Strengthening National Preparedness: BARDA’s FY23 Modernized BAA BAA-23-100-SOL-00004 – Office of Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA) In response to today’s evolving public health landscape, the Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services (HHS) within the Administration for Strategic
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Broad Agency Announcement Defense Sciences Office (DSO) Office-wide BAA Defense Sciences Office HR001125S0013 Pioneering the Next Generation of Defense Research On June 3, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Defense Sciences Office (DSO), announced an open solicitation under Broad Agency Announcement (BAA) HR001125S0013. This office-wide BAA serves as a mechanism for
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In a continued effort to bolster national preparedness against emerging biological threats, the Biomedical Advanced Research and Development Authority (BARDA) has released the Phase 2 issue of the “Biothreat Diagnostic Rapid Response” Solicitation (RPP-25-06-DxR2) on May 29, 2025, under its Rapid Response Partnership Vehicle (RRPV). BARDA is seeking to address pressing gaps in diagnostic test
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Program Overview Rads to Watts is a DARPA program dedicated to pioneering innovative methods for directly converting nuclear radiation into electricity, with a primary emphasis on radiation voltaics (also known as radiovoltaics). The program’s long-term goal is to develop radiovoltaic systems capable of transforming high-power nuclear radiation into kilowatts of electrical energy. Achieving operation at
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Advanced Disease Outbreaks Simulation Capabilities The Defense Advanced Research Projects Agency (DARPA) has issued a new Request for Information (RFI) titled “Advanced Disease Outbreaks Simulation Capabilities” (DARPA-SN-25-72). This announcement seeks insights from the research and development community on cutting-edge outbreak modeling tools to increase understanding of outbreak dynamics and improve future public health emergency preparedness.
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Defense Production Act (DPA) Title III Request for Information (RFI) on Advanced Canopy Transparencies In an effort to fortify the defense industrial base and enhance the reliability of critical aviation components, the U.S. Air Force Research Laboratory (AFRL) has issued a Request for Information (RFI) under Title III of the Defense Production Act (DPA). This
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ASPR Industrial Base Management and Supply Chain Request for Information (RFI) Understanding the RFI The Public Health Industrial Base Capabilities and Capacities: Essential Medicines RFI is seeking detailed input from domestic manufacturers and industry stakeholders to better understand the current capabilities and constraints in producing a list of 28 designated essential medicines. The scope includes
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Reimagining the Future of Vaccines: DTRA’s RAVEN RFI The Defense Threat Reduction Agency (DTRA), through its Joint Science and Technology Office (JSTO), has announced a new Request for Information (RFI) under the initiative titled Reimagining Available Vaccines and Envisioning Novelty (RAVEN). This RFI reflects DTRA’s responsibility to prepare the U.S. warfighter for current and emerging
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Promoting Domestic Production of Critical Medicines The White House is pushing to see more state-of-the-art pharmaceutical manufacturing facilities within the United States to strengthen the supply of essential medicines. On May 5, 2025, the President signed an Executive Order titled “Regulatory Relief to Promote Domestic Production of Critical Medicines.” The goal of this order is
