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EverGlade Insights

Marburg virus (MARV) and Sudan virus (SUDV) vaccines clinical trials

BARDA Issues Sources Sought Notice for Marburg Virus and Sudan Virus Vaccines

SSN_MARV__SUDV_Vaccines Purpose The Biomedical Advanced Research and Development Authority (BARDA), under the Administration for Strategic Preparedness and Response (ASPR) has issued a Sources Sought Notice (SSN). The subject of this SSN is Marburg virus (MARV) and Sudan virus (SUDV) vaccines in active or completed Phase 2 clinical trials. Insights on current and prospective MARV and […]

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pathophysiology lymphatic system and diseases

Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE)

GLIDE_ISO_ARPA-H-SOL-24-111_Final_29_OCT_2024 Program Overview An estimated 10 million Americans are impacted by primary lymphatic diseases, and lymphatic dysfunction contributes to the pathophysiology of many widespread chronic illnesses. Despite the importance of the lymphatic system in disease, there are currently zero FDA-approved treatments, medical devices, or therapies specifically targeting lymphatic growth and function. To catalyze a future

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MTEC RPP military medical needs

Medical Technology Enterprise Consortium (MTEC) Multi-Topic Request for Proposals

MTEC-FY-2025-Multi-Topic-Pre-Announcement Overview of Solicitation The Medical Technology Enterprise Consortium (MTEC) has released an exciting pre-announcement for its 2025 Multi-Topic Request for Proposals (RPP). This RPP calls for innovative medical prototypes addressing a range of focus areas critical to supporting military operations and improving healthcare delivery in challenging environments. Here’s an overview of what to expect

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curative cell therapies_DECIDE-ET_ARPA-H

Decentralized Engineering of Cells Informed by Dynamic Evidence Exploration Topic

ARPA-H_DECIDE-ET_Solicitation_DRAFT Overview of Exploration Topic Although Academic Medical Centers (AMCs) have developed many advanced therapies for rare and fatal diseases,  access to AMCs remains limited due to outdated production methods and inadequate quality validation. To enhancing quality assurance technologies at AMCs, the Advanced Research Projects Agency for Health (ARPA-H) has initiated the Decentralized Engineering of

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in silico modeling for ADME-Tox simulation

Computational ADME-Tox Analysis for Safer Therapeutics (CATALYST) Innovative Solutions Opening

CATALYST_ISO_(DRAFT) Overview of CATALYST Solicitation Current in vivo animal model testing methods often fail to predict human drug safety accurately, leading to inefficiencies and high costs. The Health Science Futures (HSF) Office of the Advanced Research projects Agency for Health (ARPA-H) has introduced the CATALYST program to transform drug development. This program will foster the

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monoclonal antibody

BARDA Announces Solicitation to Improve Monoclonal Antibody Platforms for Pre-Exposure Prophylaxis

PrEP_Solicitation_Monoclonal_Antibody_Platform_Approaches Overview of Solicitation The Biomedical Advanced Research and Development Authority (BARDA), partnered with the Vaccine Innovation and Therapeutics Accelerator Launchpad (VITAL), have announced a solicitation for proposals to address current limitations of monoclonal antibody (mAb) platforms used as pre-exposure prophylaxis (PrEP) for seasonal respiratory viruses. The solicitation focuses on advancing the development of mAb

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nucleic acid-based therapeutics

BARDA Announces Solicitation to Improve Nucleic Acid Platforms for Pre-Exposure Prophylaxis

PrEP_Solicitation_Nucleic_Acid_Platform_Approaches Overview of Solicitation The Biomedical Advanced Research and Development Authority (BARDA), partnered with the Vaccine Innovation and Therapeutics Accelerator Launchpad (VITAL), have announced a solicitation for proposals to address current limitations of long-acting nucleic acid-based platforms used as pre-exposure prophylaxis (PrEP) for seasonal respiratory viruses. The specific goals of these PrEP DEV awards include

BARDA Announces Solicitation to Improve Nucleic Acid Platforms for Pre-Exposure Prophylaxis Read More »

cancer moonshot

Cancer Moonshot and the ARPA-H Cancer Funding Landscape

Even with incredible scientific progress, cancer remains the second highest leading cause of death in the United States (U.S.) and one of the highest causes of death worldwide. To accelerate and bolster the great innovations made in therapeutics, diagnostics, and patient care, the Biden-Harris administration has reignited the Cancer Moonshot initiative. This program, introduced by

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cell therapies

ARPA-H Issues Draft Solicitation for Autologous Cell Therapy (ACT)

DECIDE_ET_Solicitation_DRAFT The Advanced Research Projects Agency for Health (ARPA-H) has introduced the Decentralized Engineering of Cells Informed by Dynamic Evidence (DECIDE) Exploration Topic (ET), representing a crucial initiative designed to revolutionize the production and validation of autologous cell therapies. This ET targets significant enhancements in the production processes at Academic Medical Centers (AMCs), focusing on

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Senior chemist analysing blood sample while working overtime in chemistry equipped laboratory.

ARPA-H Announces Proposers’ Day for New POSEIDON Program

Proposers’ Day Notice 24-SOL-109+POSEIDON+DRAFT+ISO_9+AUG+24 The Advanced Research Projects Agency for Health (ARPA-H) has recently unveiled an exciting initiative named POSEIDON (Platform Optimizing SynBio for Early Intervention and Detection in ONcology). This program aims to drastically shift the current landscape of cancer detection through innovative, synthetic biology-based approaches. As part of this groundbreaking venture, ARPA-H is

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African American woman in a technically advanced career

ARPA-H Announces Small Business Opportunities

The Advanced Research Projects Agency for Health (ARPA-H) has announced an upcoming solicitation for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) contracts for FY2024. The initiative targets innovative firms capable of conducting cutting-edge research and development, with a focus on commercializing the results. The solicitation includes opportunities for Phase I, Direct to Phase II, and Fast Track contracts.

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Abstract virus on blue background

BARDA Announces Request for Project Proposal to Establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services

Biomedical Advanced Research and Development Authority (BARDA) through the Rapid Response Partnership Vehicle (RRPV) initiative released a Request for Project Proposals (RPP) to establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services to support vaccine development and response to pandemics and emerging infectious diseases.

BARDA Announces Request for Project Proposal to Establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services Read More »

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