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A New Valley of Death? by Eric Jia-Sobota

It seems that there may be a new Valley of Death on the horizon of COVID therapeutic development. Earlier this month (9 JUL) NIAID posted a Funding Opportunities Announcement soliciting proposals related to COVID therapeutic development through their Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern program (RFA-AI-21-050: Antiviral Drug Discovery (AViDD) Centers …

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COVID-19 Antiviral Therapeutics Procurement by Eric Jia-Sobota

Earlier this month the Army Contracting Command published an amendment to solicitation W911QY-20-S-C001 related to Area of Interest 5, oral antiviral therapeutics. This is a procurement solicitation and specifically the USG is looking for direct-acting antivirals for COVID-19 high-risk patients. Successful offerors will be able to deliver 500,000 treatment courses of the anti-viral within eight …

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New Opportunity for COVID Therapeutics by Eric Jia-Sobota

For the past 18 months companies have been confused and frustrated by the shifting USG policies regarding the development of therapeutics as part of the COVID-19 response. BARDA was back and forth as parts of the BAA were suspended, unsuspended, and resuspended. The American rescue Plan legislation was passed about six months ago and although …

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ACC-JCRD seeking Commercial Solutions by Eric Jia-Sobota

The Joint Army Contracting Command and the Joint COVID Response Division (ACC-JCRD) recently published a solicitation seeking Commercial Solutions to decrease US reliance on fragile global supply chains and increase preparedness for future pandemics. The solicitation seeks to establish, expand, and accelerate the availability of domestically-produced supplies in several different areas, some of which may …

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BARDA Funding Freeze Risks Companies Abandoning COVID Therapeutic Work

Executive Summary BARDA’s suspension of funding for COVID-19 therapeutics risks repeating mistakes of past pandemics as it may cause industry to pull out of the development space, experts say. Industry sources are concerned the Biden administration is focusing on funding NIH at the expense of BARDA. The Biomedical Advanced Research and Development Authority quietly suspended …

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CEPI Funding Opportunity by Eric Jia-Sobota

Recently, the Coalition for Epidemic Preparedness Innovations (CEPI) published a call for proposals that is open from 28 JAN 2021 to 28 MAY 2021 and can be found here [CEPICfPCallText.pdf]. Trials that expand access in low and middle income countries is strongly encouraged. The objective is to expand access to vaccines that are already in …

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BARDA Opportunities: Therapeutics by Eric Jia-Sobota

Recently BARDA published information about the COVID programs the USG is supporting through collaboration between HHS and DoD. Some of that information is summarized in the  table below. In the rush to respond to the COVID pandemic the portfolio became unbalanced, especially regarding therapeutics. With the new administration there is interest and funding available to …

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BARDA Animal Model Network Solicitation by Eric Jia-Sobota

The Biomedical Advanced Research and Development Authority (BARDA) recently published a Presolicitation Notice for a project titled ‘BARDA Chemical Animal Model Development” [beta.SAM.gov | Search]. The Notice announces BARDA’s intention to publish an RFP for the same project on or around February 14, 2021. The RFP seeks proposals related to testing services, not product development. …

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HIV Prevention

USAID Opportunity: HIV Prevention

Although it may seem that COVID gets all the attention, there are still funding opportunities in other infectious disease areas. For example, the US Agency for International Development (USAID) just published an addendum to their BAA [beta.SAM.gov] regarding a program called The Microbicide 2020 R&D Project: Advancing the Research and Development of Innovative HIV Prevention …

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New Administration off to Fast Start with Flurry of Executive Orders by Eric Jia-Sobota

During his first week in office President Biden followed through on his promise for swift executive action to address COVID. One Executive Order (EO) focused on COVID care and treatments (Improving and Expanding Access to Care and Treatments for COVID-19). One section of this EO aims to accelerate the development of novel therapies. It call …

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