New NIH Funding Opportunity - Investigating the Role of Genomic Variation on Gene Regulation and Disease - EverGlade Consulting NIH Funding Opportunity

New NIH Funding Opportunity – Investigating the Role of Genomic Variation on Gene Regulation and Disease

NIH Funding

At EverGlade Consulting, we are always on the lookout for new funding opportunities that can help our clients advance their research and development goals. Today, we’re excited to inform you about a new Request for Applications (RFA) from the National Institutes of Health (NIH): RFA-HG-24-004.

NIH Funding Opportunity: Investigating the Role of Genomic Variation on Gene Regulation and Disease

Funding Opportunity Number: RFA-HG-24-004

Purpose: This RFA invites applications to investigate how genomic variation affects gene regulation and how this, in turn, contributes to human health and disease. This funding opportunity aims to support research that will lead to a better understanding of the mechanisms through which genomic variation influences gene function and regulation.

Key Dates:

  • Letter of Intent Due Date: August 9, 2024
  • Application Due Date: September 9, 2024
  • Scientific Merit Review: November 2024
  • Advisory Council Review: January 2025
  • Earliest Start Date: April 2025

Funding Information:

  • Total Funding: NIH intends to fund an estimated total of $10 million for the fiscal year 2024.
  • Number of Awards: Approximately 5-7 awards.
  • Award Budget: Application budgets are not limited but must reflect the actual needs of the proposed project.
  • Project Period: The maximum project period is 5 years.

Research Objectives

Applicants are encouraged to propose studies that leverage existing genomic data and apply innovative methods to explore:

  1. Genomic Variation: Investigate how different types of genomic variation, including single nucleotide polymorphisms (SNPs), structural variants, and epigenomic modifications, affect gene regulation.
  2. Gene Regulation Mechanisms: Elucidate the mechanisms by which genomic variation influences gene expression, including the roles of enhancers, promoters, non-coding RNAs, and other regulatory elements.
  3. Disease Mechanisms: Explore how these regulatory mechanisms contribute to the etiology of human diseases, with a focus on identifying potential therapeutic targets.


  • Eligible Applicants: Higher education institutions, nonprofits, for-profit organizations, governments, and other entities.
  • Foreign Institutions: Non-U.S. institutions are eligible to apply.

Application and Submission Information:

Applications must be submitted electronically via the NIH ASSIST system. Detailed instructions for submission, including formatting requirements and review criteria, are provided in the RFA.

Additional Information

For additional information regarding the application process and requirements, please refer to the full RFA or contact the program officer listed in the announcement.

Why This Opportunity Matters

This funding opportunity represents a significant investment by the NIH to advance our understanding of the genetic basis of disease. By exploring the intricate relationships between genomic variation, gene regulation, and disease mechanisms, this research has the potential to uncover new insights that could lead to the development of novel therapeutic strategies and improve human health.

At EverGlade Consulting, we are committed to helping our clients navigate the complexities of grant applications and maximize their chances of securing funding. If you are interested in applying for this opportunity or need assistance with your application, please do not hesitate to contact us. Our team of experts is here to support you every step of the way. If your company has considered applying for NIH funding, your federal funding journey starts here.

Collaborate With Everglade Consulting

EverGlade Consulting is a national consulting firm connecting public sector needs with private sector solutions. We offer services ranging from Pursuit, Proposal, and Post-Award support to comply with federal regulations at agencies including BARDA, ASPR, NIH, DTRA, JPEO, DOD, DOE, and DARPA.

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