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BARDA Seeks Input on Medical Countermeasures for Drug-Resistant Fungal Infections

Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) to better understand the current development landscape for antifungal medical countermeasures. BARDA plays a central role in advancing […]

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BARDA Seeks Input on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Filovirus Therapeutics

Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) focused on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses. Filoviruses, including Ebola virus (EBOV), Sudan virus

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DARPA Seeks Input on Rapid Petroleum Stabilization and Repurposing Technologies

Download the Solicitation The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released a Request for Information (RFI) titled ROUNDTOP, seeking input from industry, academia, government laboratories, and non-traditional performers. The RFI focuses on advanced methods to rapidly stabilize and/or repurpose large volumes of petroleum products, including petroleum abandoned in

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DARPA Explores Universal Biomolecule Purification Platforms Through New MTO RFI

Download the Solicitation The Defense Advanced Research Projects Agency (DARPA), through its Microsystems Technology Office (MTO), has released Request for Information (RFI) DARPA-SN-26-66 focused on biomolecule purification technologies. The RFI seeks information on novel purification methods capable of enabling a universal platform for separating and recovering multiple large and complex molecules from complex biological feedstocks

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ARPA-H’s THEA Program Seeks Breakthrough Optic Nerve Imaging Technologies

Download the Solicitation The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Mission Office, has released a Sources Sought notice titled “Novel and Enhanced Modalities for Optic Nerve Imaging” (ARPA-H-SS-26-157). This request is being issued in support of ARPA-H’s Transplantation of Human Eye Allografts (THEA) program, an ambitious initiative focused on

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ARPA-H’s HEARING Program Aims to Revolutionize Brain-Driven Hearing Restoration

The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures (HSF) Office, has released an Innovative Solutions Opening (ISO) for Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING), ARPA-H-SOL-26-154. The program seeks to fundamentally rethink hearing loss treatment by shifting the focus from the ear alone to the brain’s auditory cortex. ARPA-H estimates

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autonomous robotic systems – Untethered Robotics

Materials for Physical Compute in Untethered Robotics

DARPA-SN-26-76 In April 2026, the Defense Advanced Research Projects Agency (DARPA), through its Microsystems Technology Office (MTO), released a Request for Information (RFI) titled “Materials for Physical Compute in Untethered Robotics” (DARPA-SN-26-76). This RFI signals DARPA’s early-stage interest in advancing the next generation of autonomous robotic systems capable of operating in communication-denied and dynamically changing

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Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit)

DARPA’s O-Circuit Program and the Future of Biological Computing

DARPA-PS-26-28 In May 2026, the Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), released a new program solicitation titled Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit). This initiative reflects DARPA’s continued investment in next-generation computing paradigms, specifically those that move beyond traditional silicon-based systems. At a high

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ARPA-H Launches IGoR Program to Transform Biomedical Research Infrastructure

ARPA-H Launches IGoR Program to Transform Biomedical Research Infrastructure

ARPA-H-SOL-26-155 APPENDIX A: PROGRAM AND TECHNICAL DESCRIPTION The Advanced Research Projects Agency for Health (ARPA-H) has released the Intelligent Generator of Research (IGoR) Innovative Solutions Opening (ISO), a bold initiative designed to fundamentally transform how biomedical research is conducted. Managed through ARPA-H’s Proactive Health Office, the program seeks to address longstanding inefficiencies in scientific discovery

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DARPA’s RAPIID Program shelf stable blood analogs

DARPA’s RAPIID Program to Transform Trauma Care with Shelf-Stable Blood Analogs

DARPA-SN-26-77 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has issued Special Notice DARPA-SN-26-77 to announce forthcoming areas of interest for the Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) program. As part of DARPA’s broader mission to accelerate breakthrough technologies for national security, this initiative aims to address one of

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DARPA DICE Program

DARPA’s DICE Program

DARPA-SN-26-65 The Defense Advanced Research Projects Agency (DARPA), through its Information Innovation Office (I2O), has released a Special Notice titled Decentralized Artificial Intelligence through Controlled Emergence (DICE), DARPA-SN-26-65. This notice reflects DARPA’s ongoing mandate to pursue bold, high-impact research that delivers asymmetric advantages for national defense. With DICE, DARPA is targeting one of the most

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ARPA-H TIGAR Biopreservation

ARPA-H TIGAR Opens a New Lane for Biopreservation Innovation

ARPA-H-SOL-26-144_TIGAR ISO ARPA-H’s new Technology InteGrator and AcceleratoR (TIGAR) Innovative Solutions Opening (ISO) is a tightly scoped opportunity for government contractors and their research partners to reshape how complex biologics, tissues, and organs are stored, transported, and deployed at scale. By seeding high-risk, high-impact biopreservation concepts, TIGAR aims to unlock temperature-flexible storage for increasingly large

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