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ARPA-H

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ARPA-H’s Proactive Health Office ISO

PROACTIVE HEALTH OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-106 – Amendment 03: October 14, 2025 Building a Healthier Future Through Prevention The Advanced Research Projects Agency for Health (ARPA-H), a key innovation agency within the U.S. Department of Health and Human Services, has released an updated solicitation for its Proactive Health Office […]

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HHS Operations During A Government Shutdown

When the federal government faces a lapse in appropriations, agencies across the Department of Health and Human Services (HHS) must implement contingency plans to sustain critical activities. Both the Advanced Research Projects Agency for Health (ARPA-H) and the Administration for Strategic Preparedness and Response (ASPR), which houses the Biomedical Advanced Research and Development Authority (BARDA),

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ARPA-H THRIVE ISO

ARPA-H THRIVE_ISO_Final_16092025 Transforming Genetic Medicine for Rare Diseases: ARPA-H’s THRIVE Initiative The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Office, has announced the Treating Hereditary Rare diseases with In Vivo precision genetic mEdicines (THRIVE) Innovative Solutions Opening (ISO) (ARPA-H-SOL-25-122). The initiative represents a bold step toward curative genetic medicines that

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ARPA-H GIVE Initiative to Transform Genetic Medicine Manufacturing

ARPA-H 4.0_GIVE_ISO_20250925 Revolutionizing Biomanufacturing for Personalized Genetic Medicines The Advanced Research Projects Agency for Health (ARPA-H), through its Scalable Solutions Office (SSO), has released an Innovative Solutions Opening (ISO) titled Genetic Medicines and Individualized Manufacturing for Everyone (GIVE). This bold initiative seeks to accelerate U.S. leadership in biomanufacturing by enabling distributed, on-demand, and individualized production

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ARPA-H_Mission Office Innovative Solutions Openings (ISO)

ARPA-H Mission Office Innovative Solutions Openings (ISOs)

Overview The Advanced Research Projects Agency for Health (ARPA-H) is dedicated to accelerating transformative health solutions by tackling some of the most pressing challenges in biomedical and healthcare innovation. As part of this mission, ARPA-H has launched Mission Office Innovative Solutions Openings (ISOs) that promote the development of health technologies that lie outside of the

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ARPA-H_RAPID rare disease diagnostics

RAPID Solicitation

RAPID_SOL_25_119_FINAL Overview The Advanced Research Projects Agency for Health (ARPA-H) recently announced the newly approved program for Rare disease AI/ML for Precision Integrated Diagnostics (RAPID). The RAPID program aims to significantly improve outcomes for people with rare diseases by reducing diagnostic delays by ≥50%, decreasing misdiagnosis rates, and expanding access to diagnostics. Beyond benefitting the treatment experience of

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ARPA-H_EIH health and biomedical research

Emerging Health Innovators (EHI) Initiative

ARPA_H_SOL_25_118_EHI_Solicitation (1) Emerging Health Innovators Solicitation: An Opportunity to Revolutionize Health Innovation The Advanced Research Projects Agency for Health (ARPA-H) has issued the Emerging Health Innovators (EHI) Initiative Solicitation (ARPA-H-SOL-25-118), a groundbreaking funding opportunity aimed at empowering both early-career researchers and community innovators to advance health and biomedical research. Through the EHI Initiative, ARPA-H seeks

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ARPA-H, RAPID Funding Alert

EverGlade Consulting Funding Alert: Proposer’s Day for Rare disease AI/ML for Precision Integrated Diagnostics (RAPID)

RAPID_Special_Notice ARPA-H’s RAPID Program The Advanced Research Projects Agency for Health (ARPA-H) recently announced the newly approved program for Rare disease AI/ML for Precision Integrated Diagnostics (RAPID). This initiative aims to revolutionize the prolonged diagnostic odyssey faced by millions of rare disease patients worldwide. Utilizing fragmented datasets and state-of-the-art technologies, RAPID aims to democratize access

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ARPA-H PROSPR prolonging resilience

EverGlade Consulting Funding Alert: PROactive Solutions for Prolonging Resilience (PROSPR)

ARPA-H-SOL-25-125_Special_Notice ARPA-H’s PROSPR Program The Advanced Research Projects Agency for Health (ARPA-H) has announced the PROactive Solutions for Prolonging Resilience (PROSPR) initiative, an ambitious program designed to extend the healthspan of Americans by addressing the underlying causes of age-related health loss. By pioneering innovative interventions that target age-induced health deterioration, ARPA-H aims to revolutionize healthcare

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ACTR Initiative clinical trials

Transforming Clinical Trials with the Advancing Clinical Trial Readiness (ACTR) Initiative

ARPA-H launches groundbreaking funding opportunity The Advancing Clinical Trial Readiness (ACTR) Initiative, spearheaded by ARPA-H’s Resilient Systems Office (RSO), aims to revolutionize clinical trials by developing a decentralized, efficient, and accessible infrastructure. Overview of Solicitation The ACTR Initiative is focused on creating tools, networks, and infrastructure to enable decentralized and on-demand clinical trials. By integrating

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ARPA-H health equity, technology, and biomedical research

Emerging Health Innovators (EHI) Initiative Proposer’s Day

ARPA-H-SN-25-119 (1) The Advanced Research Projects Agency for Health (ARPA-H) has launched the Emerging Health Innovators (EHI) Initiative, a transformative funding opportunity aimed at empowering early-career researchers and community-based innovators to revolutionize healthcare. To support this initiative, ARPA-H is holding a virtual Proposer’s Day on January 8th, 2025, from 11AM to 4PM EDT. Overview of

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pathophysiology lymphatic system and diseases

Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE)

GLIDE_ISO_ARPA-H-SOL-24-111_Final_29_OCT_2024 Program Overview An estimated 10 million Americans are impacted by primary lymphatic diseases, and lymphatic dysfunction contributes to the pathophysiology of many widespread chronic illnesses. Despite the importance of the lymphatic system in disease, there are currently zero FDA-approved treatments, medical devices, or therapies specifically targeting lymphatic growth and function. To catalyze a future

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