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ARPA-H Launches REST to Transform Sleep Through Home-Based Sleep Diagnostics and Treatment

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Download the Solicitation Why ARPA-H is Seeking Solutions for Sleep Health The Advanced Research Projects Agency for Health (ARPA-H), through its Proactive Health Office (PHO), has released an Innovative Solutions Opening (ISO) for the Restorative and health-Enhancing Sleep Time (REST) program (ARPA-H-SOL-26-159). REST seeks to fundamentally change how sleep quality is measured, diagnosed, and treated by […]

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BARDA Seeks Input on Next-Generation High-Performance Antigen Diagnostics

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Download the Solicitation Overview of the RFI The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a Request for Information (RFI) titled “High Performance Antigen Diagnostics.” Through this market research effort, BARDA is seeking feedback from industry, academia, and other stakeholders to better understand the landscape of current and emerging high-performance immunoassay

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BARDA Issues RFP Under Project BioShield for 2-PAM Autoinjectors to Strengthen Chemical Threat Preparedness 

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR), has released a Request for Proposals (RFP) for 2-PAM Autoinjectors for Project BioShield. The RFP supports late-stage clinical development, regulatory approval, procurement, and delivery of pralidoxime, also known as 2-PAM, autoinjectors for the treatment of organophosphate (OP)

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BARDA Releases BundiVx Solicitation to Accelerate Bundibugyo Ebola Vaccine Development

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has officially released Request for Project Proposals (RPP) RRPV 26-13-BundiVx for the Bundibugyo Virus Outbreak Response Vaccines (BundiVx) Program. The solicitation seeks to accelerate the development of investigational vaccine candidates targeting Bundibugyo ebolavirus (BDBV), the virus responsible for

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ARPA-H’s BRAINS Initiative to Advance Functional Brain Tissue Repair

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Download the Solicitation Restoring Brain Function: ARPA-H’s BRAINS Initiative The Advanced Research Projects Agency for Health (ARPA-H) has launched the Brain Repair of Any Injured Neural Structure (BRAINS) initiative to address a major unmet need in neurological care: the lack of effective therapies to replace damaged or degenerated brain tissue and restore lost function. Brain

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BARDA Seeks Input on “Protection Before Day One” Influenza Vaccines with Pandemic Coverage

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Download the RFI Overview of the RFI The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR), has released a Request for Information (RFI) titled “Protection Before Day One Vaccine: Advancing Broadly Protective Seasonal Influenza Vaccines with Pandemic Coverage.” Through this market research effort, BARDA is seeking feedback from industry, academia, and

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DARPA Releases TA1/TA2 Solicitation for RAPIID Blood Analog Systems for Far-Forward Trauma Care

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The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released Program Solicitation DARPA-PS-26-124 for the Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) program. RAPIID aims to develop a deployable blood analog system capable of providing the life-saving functions of stored whole blood without requiring cold-chain storage or donor logistics. This

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BARDA Seeks Input on Medical Countermeasures for Drug-Resistant Fungal Infections

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) to better understand the current development landscape for antifungal medical countermeasures. BARDA plays a central role in advancing

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BARDA Seeks Input on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Filovirus Therapeutics

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Download the Solicitation The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), has issued a Request for Information (RFI) focused on AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses. Filoviruses, including Ebola virus (EBOV), Sudan virus

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DARPA Explores Universal Biomolecule Purification Platforms Through New MTO RFI

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Download the Solicitation The Defense Advanced Research Projects Agency (DARPA), through its Microsystems Technology Office (MTO), has released Request for Information (RFI) DARPA-SN-26-66 focused on biomolecule purification technologies. The RFI seeks information on novel purification methods capable of enabling a universal platform for separating and recovering multiple large and complex molecules from complex biological feedstocks

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ARPA-H’s THEA Program Seeks Breakthrough Optic Nerve Imaging Technologies

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Download the Solicitation The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Mission Office, has released a Sources Sought notice titled “Novel and Enhanced Modalities for Optic Nerve Imaging” (ARPA-H-SS-26-157). This request is being issued in support of ARPA-H’s Transplantation of Human Eye Allografts (THEA) program, an ambitious initiative focused on

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ARPA-H’s HEARING Program Aims to Revolutionize Brain-Driven Hearing Restoration

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The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures (HSF) Office, has released an Innovative Solutions Opening (ISO) for Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING), ARPA-H-SOL-26-154. The program seeks to fundamentally rethink hearing loss treatment by shifting the focus from the ear alone to the brain’s auditory cortex. ARPA-H estimates

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