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Life Sciences

Medicine manufacturing assembly line.

ARPA-H’s Scalable Solutions ISO

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Mission Office Innovative Solutions Opening (ISO)– ARPA-H-SOL-24-105 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) officially released solicitation ARPA-H-SOL-24-105 under its Scalable Solutions Office (SSO), titled Mission Office Innovative Solutions Opening (ISO). This initiative aims to fuel bold, high-impact biomedical and health innovations that tackle persistent barriers in health […]

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Medicine production on conveyor belt

IBMSC RISE OTA Consortium RFI

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Request for Information – IBMSC Resilient Industry and Supply Chain Enterprise (RISE) OTA Consortium In June 2025, the U.S. Department of Health and Human Services (HHS) issued a Request for Information (RFI) through the Administration for Strategic Preparedness and Response’s (ASPR) Center for Industrial Base Management and Supply Chain (IBMSC). This RFI invites feedback from

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ARPA-H’s Proactive Health Office ISO Amendment 2

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PROACTIVE HEALTH OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-106 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has recently amended the Proactive Health Office (PHO) Innovative Solutions Opening (ISO). The PHO ISO invites novel and disruptive health innovations aimed at extending health spans and improving health

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ARPA-H Resilient Systems ISO

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RESILIENT SYSTEMS OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-103 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Innovative Solutions Opening (ISO) under the Resilient Systems Office (RSO), under Solicitation Number ARPA-H-SOL-24-103. a mission-focused solicitation designed to confront systemic challenges across

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ARPA-H Health Science Futures ISO

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Health Science Futures – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) ARPA-H-SOL-24-104 – Amendment 02: June 06, 2025 The Advanced Research Projects Agency for Health (ARPA-H) has released Amendment 02 of its Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO), under Solicitation Number ARPA-H-SOL-24-104. As part of its mission to catalyze high-risk, high-reward research,

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ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

ARPA-H’s Four Mission Offices Sharpen Their Vision with ISO Amendments

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On June 6, 2025, the Advanced Research Projects Agency for Health (ARPA-H) issued Amendment 02 to its four flagship Innovation Solutions Opening (ISO) solicitations: Health Science Futures (HSF), Proactive Health Office (PHO), Resilient Systems Office (RSO), and Scalable Solutions Office (SSO). These ISOs represent the core operational arms of ARPA-H’s mission to fund transformative, high-risk,

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Vaccine Research

Strengthening National Preparedness: BARDA’s FY23 Modernized BAA

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Strengthening National Preparedness: BARDA’s FY23 Modernized BAA BAA-23-100-SOL-00004 – Office of Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA) In response to today’s evolving public health landscape, the Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services (HHS) within the Administration for Strategic

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Rapid Response Test

BARDA’s DxR2 RPP: Scaling Biothreat Diagnostic Readiness

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In a continued effort to bolster national preparedness against emerging biological threats, the Biomedical Advanced Research and Development Authority (BARDA) has released the Phase 2 issue of the “Biothreat Diagnostic Rapid Response” Solicitation (RPP-25-06-DxR2) on May 29, 2025, under its Rapid Response Partnership Vehicle (RRPV). BARDA is seeking to address pressing gaps in diagnostic test

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ASPR RFI: Public Health Industrial Base Capabilities and Capacities: Essential Medicines

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ASPR Industrial Base Management and Supply Chain Request for Information (RFI) Understanding the RFI The Public Health Industrial Base Capabilities and Capacities: Essential Medicines RFI is seeking detailed input from domestic manufacturers and industry stakeholders to better understand the current capabilities and constraints in producing a list of 28 designated essential medicines. The scope includes

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Close-up of Medical Ampoule Production Line at Modern Modern Pharmaceutical Factory. Glass Ampoules are being Filled. Medication Manufacturing Process.

DTRA’s RAVEN RFI Seeks Multivalent Vaccine Innovation

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Reimagining the Future of Vaccines: DTRA’s RAVEN RFI The Defense Threat Reduction Agency (DTRA), through its Joint Science and Technology Office (JSTO), has announced a new Request for Information (RFI) under the initiative titled Reimagining Available Vaccines and Envisioning Novelty (RAVEN). This RFI reflects DTRA’s responsibility to prepare the U.S. warfighter for current and emerging

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The White House Initiatives

White House Unveils New Initiatives for Critical Medicines and Biological Research Safety

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Promoting Domestic Production of Critical Medicines The White House is pushing to see more state-of-the-art pharmaceutical manufacturing facilities within the United States to strengthen the supply of essential medicines. On May 5, 2025, the President signed an Executive Order titled “Regulatory Relief to Promote Domestic Production of Critical Medicines.” The goal of this order is

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DoD Seeks Host-Directed Therapeutics to Counter Emerging Biological Threats

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A New Direction: Host-Directed, Not Pathogen-Specific Unlike traditional antivirals or antibiotics, host-directed therapeutics (HDTs) focus on modulating the patient’s immune response rather than targeting a specific pathogen. This “threat-agnostic” approach is especially promising in an era marked by evolving biological agents and unpredictable infectious threats. The DoD is particularly interested in repurposed FDA-approved therapeutics or

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