September 30, 2026 - EverGlade

September 30, 2026

ARPA-H Launches SURPASS to Advance Simulation-Augmented, Real-Time Adaptive Clinical Trials

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The Advanced Research Projects Agency for Health’s (ARPA-H) Proactive Health Office has released Innovative Solutions Opening (ISO) ARPA-H SOL 26 164 for the Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) program. SURPASS seeks to establish persistent, multi-arm clinical trial platforms that integrate simulation, accumulating human data, prespecified adaptations, shared operational infrastructure, and reusable regulatory assets.

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BARDA’s “Protection Before Day One” Initiative Seeks Broadly Protective Influenza Vaccines

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The Biomedical Advanced Research and Development Authority (BARDA), through the Rapid Response Partnership Vehicle (RRPV), has released a draft Request for Project Proposals (RPP) for “Protection Before Day One” (PBD1), Solicitation No. RRPV 26-08-PBD1. The initiative seeks to close a central pandemic preparedness gap: the time between identifying a novel pandemic influenza strain and deploying

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DARPA APM Solicitation Opens for Programmable Precision Polymers

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The Defense Advanced Research Projects Agency’s (DARPA) Multi X Office has released the official solicitation for Atomically Precise Molecules (APM), seeking new polymer synthesis approaches that can deliver precisely controlled materials with breakthrough nonlinear optical performance. Required proposal abstracts are due October 27, 2026, at 1:00 p.m. ET, with full proposals due December 18, 2026,

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