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PAHPA program funding

After the CR: Funding Opportunities and Gaps in Pandemic Preparedness

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Congress’s passage of a continuing resolution (CR) has averted a shutdown and provided temporary relief until late March. However, this short-term fix exposes significant gaps in public health and technology preparedness that demand immediate attention. As critical programs approach expiration and threats beyond the Pandemic and All-Hazards Preparedness Act (PAHPA) remain unresolved, lawmakers have a […]

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drug-resistant bacterial infections

BARDA Antibiotic for Treatment of Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia or Bloodstream Infections Caused by Drug-Resistant Bacteria or Biothreat Pathogens

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PBS+AMR+2025+SSN+-+Final The Biomedical Advanced Research and Development Authority (BARDA) has issued a Sources Sought Notice (SSN) to gather insights from antibiotic developers working on solutions for drug-resistant bacterial infections. This SSN is part of BARDA’s Antimicrobial Resistance (AMR) Project BioShield, which focuses on understanding the current antibiotic landscape and potentially facilitating future acquisitions to combat

BARDA Antibiotic for Treatment of Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia or Bloodstream Infections Caused by Drug-Resistant Bacteria or Biothreat Pathogens Read More »

Marburg virus (MARV) and Sudan virus (SUDV) vaccines clinical trials

BARDA Issues Sources Sought Notice for Marburg Virus and Sudan Virus Vaccines

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SSN_MARV__SUDV_Vaccines Purpose The Biomedical Advanced Research and Development Authority (BARDA), under the Administration for Strategic Preparedness and Response (ASPR) has issued a Sources Sought Notice (SSN). The subject of this SSN is Marburg virus (MARV) and Sudan virus (SUDV) vaccines in active or completed Phase 2 clinical trials. Insights on current and prospective MARV and

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monoclonal antibody

BARDA Announces Solicitation to Improve Monoclonal Antibody Platforms for Pre-Exposure Prophylaxis

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PrEP_Solicitation_Monoclonal_Antibody_Platform_Approaches Overview of Solicitation The Biomedical Advanced Research and Development Authority (BARDA), partnered with the Vaccine Innovation and Therapeutics Accelerator Launchpad (VITAL), have announced a solicitation for proposals to address current limitations of monoclonal antibody (mAb) platforms used as pre-exposure prophylaxis (PrEP) for seasonal respiratory viruses. The solicitation focuses on advancing the development of mAb

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nucleic acid-based therapeutics

BARDA Announces Solicitation to Improve Nucleic Acid Platforms for Pre-Exposure Prophylaxis

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PrEP_Solicitation_Nucleic_Acid_Platform_Approaches Overview of Solicitation The Biomedical Advanced Research and Development Authority (BARDA), partnered with the Vaccine Innovation and Therapeutics Accelerator Launchpad (VITAL), have announced a solicitation for proposals to address current limitations of long-acting nucleic acid-based platforms used as pre-exposure prophylaxis (PrEP) for seasonal respiratory viruses. The specific goals of these PrEP DEV awards include

BARDA Announces Solicitation to Improve Nucleic Acid Platforms for Pre-Exposure Prophylaxis Read More »

mRNA infectious diseases vaccine development

BARDA Issues RPP for Rapid Pandemic Influenza and Emerging Infectious Disease Vaccine Development and Response Capability

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24-08-mRNALongTerm_Final The Biomedical Advanced Research and Development Authority (BARDA) has released a Request for Project Proposals (RPP) aimed at vaccine development and response for emerging infectious diseases and rapid pandemic influenza. The RPP, numbered RRPV-24-08-mRNALongTerm, focuses on creating a lasting partnership that builds and maintains a robust mRNA preparedness and response system for pandemic influenza

BARDA Issues RPP for Rapid Pandemic Influenza and Emerging Infectious Disease Vaccine Development and Response Capability Read More »

biologics

BARDA Issues RPP for On-Demand Manufacturing

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RPP-24-02-ODM The Biomedical Advanced Research and Development Authority (BARDA) has released an essential Request for Project Proposals (RPP) aimed at the preparation for and response to public health emergencies through On-Demand Manufacturing. The RPP, numbered 24-02-ODM, focuses advancing manufacturing technologies that will improve access and enable faster, cheaper, more rapid, and flexible production of vaccines

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A closeup shot of a scientist conducting the gel electrophoresis biological process as part of coronavirus research

BARDA Announces Request for Project Proposals for Small Molecule Drugs

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BARDA RRPV 24-03-SmMol The Biomedical Advanced Research and Development Authority (BARDA) has released a Request for Project Proposals (RPP) under the Rapid Response Partnership Vehicle (RRPV) for developing small molecule therapeutics aimed at COVID-19 Pre-exposure Prophylaxis (PrEP). This initiative enhances national health security by advancing medical countermeasures against SARS-CoV-2 and future health threats. BARDA’s call

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BioMaP-RPP-N95-respirators

BARDA Issues RPP for N95 Respirator Production

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BioMaP_RPP_24-05-N95 The Biomedical Advanced Research and Development Authority (BARDA) has released an essential Request for Project Proposals (RPP) aimed at sustaining the manufacturing capacity of N95 respirators, a crucial element in the biopharmaceutical and healthcare sectors, especially highlighted during the COVID-19 pandemic. The RPP, numbered 24-05-N95, focuses on maintaining a “warm-base” status of manufacturing capabilities

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Single-dose Vaccine

BARDA Issues RFI for Developing Single-Dose Pandemic Influenza Vaccine

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The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration
for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human
Services (HHS), is seeking innovative ideas and strategies to develop a single-dose vaccine for pandemic
influenza. This Request for Information (RFI) is designed to gather valuable insights from
biopharmaceutical companies, research institutions, and vaccine development experts to facilitate the
creation of a vaccine that offers durable immunity with a single administration.

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Filovirus Monoclonal Antibodies

BARDA Announces RPP for Manufacturing Optimization for Filovirus Monoclonal Antibodies

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The Biomedical Advanced Research and Development Authority (BARDA) has issued a Request for Project Proposals (RPP) for “Manufacturing Optimization for Filovirus Monoclonal Antibodies.” The RPP was released on June 24, 2024, with proposals due by July 22, 2024. This initiative aims to enhance the manufacturing development of monoclonal antibody (mAb) cocktails targeting filoviruses like Ebola and Marburg viruses.

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Abstract virus on blue background

BARDA Announces Request for Project Proposal to Establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services

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Biomedical Advanced Research and Development Authority (BARDA) through the Rapid Response Partnership Vehicle (RRPV) initiative released a Request for Project Proposals (RPP) to establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services to support vaccine development and response to pandemics and emerging infectious diseases.

BARDA Announces Request for Project Proposal to Establish Central Influenza and Emerging Infectious Diseases Vaccine Immunogenicity Laboratory Services Read More »

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