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DARPA’s Biological Technologies Office Broad Agency Announcement

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DARPA BTO Broad Agency Announcement 10.25 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released a new Broad Agency Announcement (BAA), HR001126S0003, on October 1, 2025. This solicitation seeks transformative research leveraging biological processes and technologies to enhance warfighter protection and performance. DARPA BTO continues to push the boundaries […]

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US_UK Technology Prosperity Deal

The U.S.–U.K. Technology Prosperity Deal: A Strategic Framework for Shared Innovation

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On September 18, 2025, the Governments of the United States and the United Kingdom signed a Memorandum of Understanding Between the Government of the United States of America and the Government of the United Kingdom of Great Britain and Northern Ireland Regarding the Technology Prosperity Deal. This MOU reflects both countries’ commitment to partnering on

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DARPA’s MASH Program: Autonomous Trauma Care for the Battlefield

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DARPA-PS-25-34 (2) Medics Autonomously Stopping Hemorrhage (MASH) The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has announced the Medics Autonomously Stopping Hemorrhage (MASH) program (DARPA-PS-25-34). This initiative targets one of the leading causes of preventable battlefield deaths: non-compressible torso hemorrhage (NCTH). With nearly a quarter of combat fatalities in recent

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DOE unveils $1B in critical mineral funding

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Introduction The U.S. Department of Energy (DOE) has announced nearly $1 billion in funding to strengthen domestic critical minerals supply chains. This initiative targets mining, processing, and manufacturing technologies for essential materials such as rare earths, battery components, and specialty elements. It represents a major opportunity for companies prepared to advance clean energy, semiconductors, and

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DARPA NODES

DARPA Launches NODES to Revolutionize Protein Function Prediction

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DARPA-PS-25-30 Program Solicitation Network of Optimal Dynamic Energy Signatures (NODES) On July 31, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), released a new program solicitation titled Network of Optimal Dynamic Energy Signatures (NODES). This initiative seeks to unlock a deeper understanding of protein functions by moving beyond static

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protein moecules

DARPA’s NODES Program to Decode the Protein Universe Through AI and Biophysics

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The Defense Advanced Research Projects Agency (DARPA) has launched a new initiative to advance the understanding of protein molecular function based on sequence and structural data. With over 300 million protein sequences and structures cataloged, but only 1% functionally characterized, DARPA’s Network of Optimal Dynamic Energy Signatures (NODES) program seeks to transform our ability to

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Protein sequencing machine

DARPA PROSE Program: Enabling the Next Leap in Protein Sequencing Technology

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Program Announcement PROtein SEquencing (PROSE) Microsystems Technology Office The Defense Advanced Research Projects Agency (DARPA), through its Microsystems Technology Office (MTO), has issued a new Program Announcement (DARPA-PA-25-06) for its PROtein SEquencing (PROSE) initiative. This bold program seeks to overcome longstanding challenges in protein sequencing by investing in novel microsystems and signal processing architectures. PROSE

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Cortisol molecule

DARPA’s CoasterChase Initiative

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CoasterChase – BIOLOGICAL TECHNOLOGIES OFFICE – HR001125S0014 Targeting Stress from the Inside Out: DARPA’s CoasterChase Initiative The Defense Advanced Research Projects Agency (DARPA) continues to push the boundaries of biomedical technology with the release of its latest Broad Agency Announcement (BAA), HR001125S0014, titled CoasterChase. Issued by DARPA’s Biological Technologies Office (BTO), this program seeks to

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DARPA’s Ag x BTO Special Topic Calls for Agricultural Defense Innovations

DARPA’s Ag x BTO Special Topic Calls for Agricultural Defense Innovations

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Special Topic: Ag x BTO To defend against threats to America’s agricultural infrastructure, the Defense Advanced Research Projects Agency (DARPA) has launched a new Special Topic Area (STA) through its Biological Technologies Office (BTO). Known as Ag x BTO, this initiative seeks to catalyze innovative approaches to defending the U.S. agricultural system from chemical, biological,

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Superconductor microchip with blue overlay

Unlocking Scientific Breakthroughs for National Security: DARPA’s DSO Office-wide BAA

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Broad Agency Announcement Defense Sciences Office (DSO) Office-wide BAA Defense Sciences Office HR001125S0013 Pioneering the Next Generation of Defense Research On June 3, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Defense Sciences Office (DSO), announced an open solicitation under Broad Agency Announcement (BAA) HR001125S0013. This office-wide BAA serves as a mechanism for

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radiation voltaics

Rads to Watts Proposers Day

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Program Overview Rads to Watts is a DARPA program dedicated to pioneering innovative methods for directly converting nuclear radiation into electricity, with a primary emphasis on radiation voltaics (also known as radiovoltaics). The program’s long-term goal is to develop radiovoltaic systems capable of transforming high-power nuclear radiation into kilowatts of electrical energy. Achieving operation at

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Two scientists in lab coats at a computer discussing their findings

DARPA’s RFI on Advanced Disease Outbreak Simulation

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Advanced Disease Outbreaks Simulation Capabilities The Defense Advanced Research Projects Agency (DARPA) has issued a new Request for Information (RFI) titled “Advanced Disease Outbreaks Simulation Capabilities” (DARPA-SN-25-72). This announcement seeks insights from the research and development community on cutting-edge outbreak modeling tools to increase understanding of outbreak dynamics and improve future public health emergency preparedness.

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