Max Higgins, Consultant

ARPA-H-SOL-26-142_ADVOCATE+ISO ARPA-H Launches ADVOCATE to Transform Cardiovascular Care with Agentic AI The Advanced Research Projects Agency for Health (ARPA-H) has released a new Innovative Solutions Opening (ISO), Agentic AI-Enabled Cardiovascular Care Transformation (ADVOCATE), aimed at fundamentally modernizing how chronic cardiovascular disease (CVD) is managed in the United States. Announced by ARPA-H’s Scalable Solutions Office (SSO), […]

BOSS_ISO_Final_01Dec2025 The Advanced Research Projects Agency for Health (ARPA-H) has announced a landmark Innovative Solutions Opening (ISO) for the BioStabilization Systems (BoSS) program, an ambitious effort to revolutionize how live cell-based therapies are stabilized, manufactured, and distributed. As outlined in the solicitation, BoSS aims to eliminate the field’s dependence on ultra-cold storage and transport, which

ARPA-H-RFS-EVIDENT-TA-1-3-Exploratory_Clean ARPA-H’s EVIDENT Program Seeks Objective Clinical Endpoints for Rapid-Acting Behavioral Health Treatments (1) Mental and behavioral health disorders, including depression, anxiety, and addiction, affect about half of all Americans, with treatment costs nearing $200 billion annually.  Yet, traditional diagnostics still rely heavily on subjective endpoints that fail to capture the complexity and immediacy of