Max Higgins, Consultant, Author at EverGlade Consulting

Max Higgins, Consultant

Max Higgins, Consultant

NIH’s New Policy on AI and Proposal Limits: What You Need to Know

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NIH just released NOT-OD-25-132: “Supporting Fairness and Originality in NIH Research Applications.” There are two major changes that will shape how you plan and submit proposals beginning September 25, 2025: Originality & AI: NIH reiterates that applications must be the investigators’ original work and flags risks from AI-generated text (e.g., plagiarism, fabricated citations). Institutions should […]

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BARDA’s mAb “Smart Manufacturing” Opportunity

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Background The Biomedical Advanced Research and Development Authority (BARDA) within the Administration for Strategic Preparedness and Response (ASPR) has released a Draft Statement of Objectives (SOO) for feedback to help refine requirements for the upcoming “Smart Manufacturing” solicitation aiming to support the development of advanced monoclonal antibody (mAb) manufacturing and development techniques. The solicitation’s overarching

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DOE unveils $1B in critical mineral funding

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Introduction The U.S. Department of Energy (DOE) has announced nearly $1 billion in funding to strengthen domestic critical minerals supply chains. This initiative targets mining, processing, and manufacturing technologies for essential materials such as rare earths, battery components, and specialty elements. It represents a major opportunity for companies prepared to advance clean energy, semiconductors, and

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Inside the New Executive Order on Strategic API Reserves

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Introduction On August 13, 2025, President Trump signed a sweeping Executive Order titled “Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve.” The order addresses a long-standing vulnerability in the U.S. healthcare system, the nation’s heavy reliance on foreign suppliers for the active pharmaceutical ingredients (APIs) that make up the

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DTRA’s “Plume” RFI for Marine Toxin Aerosol Exposure Models

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Advancing Countermeasures for Marine Toxin Threats The Defense Threat Reduction Agency (DTRA), through its Research and Development Chemical and Biological Technologies Directorate in support of the Joint Science and Technology Office (JSTO), has issued a Request for Information (RFI) titled “Plume”. This initiative seeks information on the capabilities and availability of suitable animal models for

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Navigating the SF-1408: A Guide to Pre-Award Accounting System Approval

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For companies eager to break into the federal market, the compliance landscape can feel like a maze of unfamiliar acronyms and requirements. One of the earliest and most critical checkpoints in this journey is the SF-1408: Pre-Award Survey of Prospective Contractor’s Accounting System. If you are bidding on a cost-reimbursement or time-and-materials contract, you will

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BARDA’s Onshoring of Viral Hemorrhagic Fevers Vaccine Candidates

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As the global health landscape evolves, so too must the United States’ ability to respond rapidly to biological threats. To strengthen its readiness posture, the Biomedical Advanced Research and Development Authority (BARDA), in coordination with the Administration for Strategic Preparedness and Response (ASPR), has released a new opportunity under the BioMaP Consortium OT Vehicle. This

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DARPA NODES

DARPA Launches NODES to Revolutionize Protein Function Prediction

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DARPA-PS-25-30 Program Solicitation Network of Optimal Dynamic Energy Signatures (NODES) On July 31, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), released a new program solicitation titled Network of Optimal Dynamic Energy Signatures (NODES). This initiative seeks to unlock a deeper understanding of protein functions by moving beyond static

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DTRA RAVEN Program

DTRA’s Reimagining the Next Generation of Biodefense Vaccines

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Reimagining the Next Generation of Biodefense Vaccines: DTRA’s RAVEN Opportunity The Defense Threat Reduction Agency (DTRA), through its Joint Science and Technology Office (JSTO) and the Research and Development-Chem/Bio Medical Vaccines (RD-CBMV) division, has launched the Reimagining Available Vaccines and Envisioning Novelty (RAVEN) initiative. This forward-looking program is designed to modernize the nation’s medical countermeasure

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JPEO RFI u.s. military protective systems

U.S. Army Seeks Breakthrough Concepts to Combat Contaminant Infiltration in Protective Systems

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Overview In a Request for Information (RFI), the Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Protection (JPM CBRN P), has called on industry, academia, and non-traditional innovators to help reimagine how protective gear prevents the infiltration of harmful airborne particles and vapors. This initiative aims to address a longstanding issue known as the

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protein moecules

DARPA’s NODES Program to Decode the Protein Universe Through AI and Biophysics

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The Defense Advanced Research Projects Agency (DARPA) has launched a new initiative to advance the understanding of protein molecular function based on sequence and structural data. With over 300 million protein sequences and structures cataloged, but only 1% functionally characterized, DARPA’s Network of Optimal Dynamic Energy Signatures (NODES) program seeks to transform our ability to

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Enzyme structure with biological concept 3d rendering

BARDA Solicits Enzymatic Debridement Solutions

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BARDA RFP – Enzymatic Debridement Products for Treatments of Deep and Full- Thickness Severe Burn Injuries – 75A50125R00007 – Amendment 0001 The Biomedical Advanced Research and Development Authority (BARDA), a division of the U.S. Department of Health and Human Services (HHS), has released a significant new opportunity to strengthen national preparedness for burn mass casualty

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