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BARDA advancing pathogen agnostic diagnostics

Advancing Pathogen-Agnostic Diagnostics

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BARDA RRPV-26-09-AgDx Request for Project Proposals The Biomedical Advanced Research and Development Authority (BARDA) has released a new Request for Project Proposals (RPP-26-09-AgDx) through the Rapid Response Partnership Vehicle (RRPV), seeking to revolutionize the nation’s diagnostic readiness for infectious disease threats. Managed by Advanced Technology International (ATI), the RRPV enables collaboration between industry, academia, and […]

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BARDA’s RPP to Onshore Vaccine Manufacturing for Viral Hemorrhagic Fevers

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The Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services (HHS), has issued a new Request for Project Proposals (RPP-26-10-VHF) under its Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium). This solicitation represents a key step in building domestic capacity for advanced vaccine manufacturing to strengthen the nation’s biosecurity infrastructure.

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ARPA-H THRIVE ISO Amendment 1

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THRIVE+ISO_Amendment_No_1_Tracked_Changes (1) Amendment released for ARPA-H’s THRIVE Initiative The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Office, released Amendment No. 1 for the Treating Hereditary Rare diseases with In Vivo precision genetic mEdicines (THRIVE) Innovative Solutions Opening (ISO) (ARPA-H-SOL-25-122) on October 17, 2025. The updates focus on changes to the

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ARPA-H’s Proactive Health Office ISO

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PROACTIVE HEALTH OFFICE – MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO) – ARPA-H-SOL-24-106 – Amendment 03: October 14, 2025 Building a Healthier Future Through Prevention The Advanced Research Projects Agency for Health (ARPA-H), a key innovation agency within the U.S. Department of Health and Human Services, has released an updated solicitation for its Proactive Health Office

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HHS Operations During A Government Shutdown

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When the federal government faces a lapse in appropriations, agencies across the Department of Health and Human Services (HHS) must implement contingency plans to sustain critical activities. Both the Advanced Research Projects Agency for Health (ARPA-H) and the Administration for Strategic Preparedness and Response (ASPR), which houses the Biomedical Advanced Research and Development Authority (BARDA),

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ARPA-H THRIVE ISO

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ARPA-H THRIVE_ISO_Final_16092025 Transforming Genetic Medicine for Rare Diseases: ARPA-H’s THRIVE Initiative The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Office, has announced the Treating Hereditary Rare diseases with In Vivo precision genetic mEdicines (THRIVE) Innovative Solutions Opening (ISO) (ARPA-H-SOL-25-122). The initiative represents a bold step toward curative genetic medicines that

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ARPA-H GIVE Initiative to Transform Genetic Medicine Manufacturing

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ARPA-H 4.0_GIVE_ISO_20250925 Revolutionizing Biomanufacturing for Personalized Genetic Medicines The Advanced Research Projects Agency for Health (ARPA-H), through its Scalable Solutions Office (SSO), has released an Innovative Solutions Opening (ISO) titled Genetic Medicines and Individualized Manufacturing for Everyone (GIVE). This bold initiative seeks to accelerate U.S. leadership in biomanufacturing by enabling distributed, on-demand, and individualized production

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Advancing Biodefense Readiness: MTEC and DTRA’s Multi-Topic RPP

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In September 2025, the Medical Technology Enterprise Consortium (MTEC), in partnership with the Defense Threat Reduction Agency (DTRA), announced a new Request for Project Proposals (RPP) aimed at accelerating U.S. biodefense capabilities. The solicitation, “Advancing Biodefense Readiness: On-Demand Biologics, Automated Threat Detection, and Alternatives for Testing Medical Countermeasures in High Containment,” seeks applied prototype solutions

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Broad Spectrum Prophylactics for Acetylcholinesterase Inhibitors

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The Medical CBRN Defense Consortium (MCDC), in collaboration with the Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND), has released a Request for Information (RFI) to assess industry capabilities in developing broad spectrum prophylactic medical countermeasures (MCMs) against acetylcholinesterase (AChE) inhibitors. These inhibitors, chemical agents that can severely impair nervous system

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BARDA Issues New RPP to Advance Smart Manufacturing for Antibodies

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Driving Innovation in Antibody Manufacturing The Biomedical Advanced Research and Development Authority (BARDA) has launched a new Request for Project Proposals (RPP) aimed at transforming the speed, efficiency, and resilience of antibody (Ab) production. Issued under the Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium), the initiative seeks to integrate advanced manufacturing technologies into Ab production systems to

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DTRA–MTEC Pre-Announcement for Biodefense Readiness RPP

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MTEC-25-DTRA Pre-Announcement: Advancing Biodefense Readiness The Medical Technology Enterprise Consortium (MTEC), in support of the Defense Threat Reduction Agency (DTRA), has issued a pre-announcement for an upcoming Request for Project Proposals (RPP). This RPP will be aimed at accelerating medical countermeasures (MCMs) and fieldable biosurveillance technologies across the Chemical and Biological Defense Program. In brief,

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ASPR RFI on Essential Medicines Industrial Base

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ASPR Industrial Base Management and Supply Chain Request for Information (RFI) Strengthening the U.S. Pharmaceutical Supply Chain: ASPR’s Essential Medicines RFI The U.S. Department of Health and Human Services (HHS), through its Administration for Strategic Preparedness and Response (ASPR), recently issued a Request for Information (RFI) to industry partners regarding domestic manufacturing capabilities for essential

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