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DARPA

DARPA’s O-CIRCUIT Special Notice

DARPA’s O-CIRCUIT Special Notice Signals a New Frontier in Low-Power Biological Computing

DARPA-SN-26-48 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has issued Special Notice DARPA-SN-26-48 to alert the research community to a forthcoming program titled Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-CIRCUIT). This notice gives early visibility into a program that aims to explore an unconventional but […]

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DARPA’s Virtual-Integrated Twin

DARPA’s Virtual-Integrated Twin for Autonomous Lifesaving

DARPA-SN-26-50 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has issued Special Notice DARPA-SN-26-50 announcing additional research areas of interest for the forthcoming Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) program. This Special Notice serves as public notification ahead of a formal solicitation that will be released on SAM.gov. DARPA’s overarching

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DARPA BORDEAUX Program

DARPA’s BORDEAUX Program to Advance Cyber Security Performance in Artificial Intelligence

DARPA-PS-26-20 The Defense Advanced Research Projects Agency (DARPA), through its Information Innovation Office (I2O), has released Program Solicitation DARPA-PS-26-20 for the BORDEAUX program. DARPA, the Department of Defense’s (DoD) premier research and development agency, is charged with making pivotal early technology investments that create technological surprise for national security. With BORDEAUX, DARPA is soliciting innovative

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DARPA’s PICASSO Program

DARPA’s PICASSO Program

DARPA-PS-26-13-Amendment-01 The Defense Advanced Research Projects Agency (DARPA), through its Microsystems Technology Office (MTO), has released a new program solicitation for Photonic Integrated Circuit Architectures for Scalable System Objectives (PICASSO). This solicitation reflects DARPA’s continued interest in unlocking transformational system-level performance gains by rethinking how emerging technologies are architected, rather than incrementally improved. With PICASSO,

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DARPA MARRS to Advance Solid-State Fusion at Room Temperature

DARPA Launches MARRS to Advance Solid-State Fusion at Room Temperature

Broad Agency Announcement: MARRS HR001126S0007 The Defense Advanced Research Projects Agency (DARPA) has released a new Broad Agency Announcement (BAA) under its Defense Sciences Office (DSO) titled Mechanisms for Amplification of Fusion Reaction Rates in Solids (MARRS). Through MARRS, DARPA seeks to explore whether nuclear fusion reactions operating at or near room temperature in solid

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DARPA’s Generative Optogenetics (GO) Program

DARPA’s Generative Optogenetics (GO) Program

DARPA-PS-26-10 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released a new program solicitation for Generative Optogenetics (GO), a bold, high-risk, high-reward research effort aimed at redefining how genetic information is delivered to living cells. Announced on December 19, 2025, this solicitation reflects DARPA’s continued investment in foundational biological

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DARPA BAA Information Innovation

DARPA I2O Office-Wide BAA Opens the Door for Breakthroughs in Information Innovation

DARPA Broad Agency Announcement HR001126S0001 The Defense Advanced Research Projects Agency (DARPA), through its Information Innovation Office (I2O), has released its FY2026 Office-Wide Broad Agency Announcement (BAA) seeking groundbreaking research that can fundamentally reshape the nation’s capabilities across information science, cybersecurity, artificial intelligence (AI), and complex software systems. This solicitation, HR001126S0001, invites performers to propose

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DARPA smart red cells program

DARPA’s Smart Red Blood Cells Program: Engineering the Future of Human Performance

DARPA-PS-26-02 (Smart Red Blood Cells Program) The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has announced a groundbreaking solicitation titled DARPA-PS-26-02: Smart Red Blood Cells (Smart-RBC) to redefine human performance in extreme environments. This program seeks to leverage advances in synthetic biology and bioengineering to create red blood cells (RBCs)

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DARPA Disruptioneering Program

DARPA’s Disruptioneering Program

DARPA Disruptioneering Program Announcement 25-07 The Defense Advanced Research Projects Agency (DARPA), through its Defense Sciences Office (DSO), has released its latest Disruptioneering Program Announcement (DARPA-PA-25-07). Published on September 30, 2025, this initiative aims to accelerate the agency’s ability to fund and execute high-risk, high-reward scientific research. At its core, the Disruptioneering program establishes a

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DARPA’s Biological Technologies Office Broad Agency Announcement

DARPA BTO Broad Agency Announcement 10.25 The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has released a new Broad Agency Announcement (BAA), HR001126S0003, on October 1, 2025. This solicitation seeks transformative research leveraging biological processes and technologies to enhance warfighter protection and performance. DARPA BTO continues to push the boundaries

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DARPA’s MASH Program: Autonomous Trauma Care for the Battlefield

DARPA-PS-25-34 (2) Medics Autonomously Stopping Hemorrhage (MASH) The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), has announced the Medics Autonomously Stopping Hemorrhage (MASH) program (DARPA-PS-25-34). This initiative targets one of the leading causes of preventable battlefield deaths: non-compressible torso hemorrhage (NCTH). With nearly a quarter of combat fatalities in recent

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DARPA NODES

DARPA Launches NODES to Revolutionize Protein Function Prediction

DARPA-PS-25-30 Program Solicitation Network of Optimal Dynamic Energy Signatures (NODES) On July 31, 2025, the Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), released a new program solicitation titled Network of Optimal Dynamic Energy Signatures (NODES). This initiative seeks to unlock a deeper understanding of protein functions by moving beyond static

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